Erkki Kolehmainen

No active affiliation

Research interests

Sappihapot ovat steroidirunkoisia hydroksihappoja, jotka syntyvät kolesterolista maksasassa ja suolistossa. Sappihappojen tehtävänä on tehostaa rasvojen ja rasvaliukoisten vitamiinien imeytymistä. Sen lisäksi sappihapoilla on havaittu hormonaalista vaikutusta ja niillä on potentiaalia myös metabolisen oireyhtymän ja diabeteksen hoidossa. Huonosti imeytyvien lääkeaineiden biosaatavuutta voidaan parantaa sitomalla ne sappihappoihin ns. aihiolääkkeiksi. Niin ollen sappihappotukimuksella on akateemisen mielenkiinnon ja haasteellisuuden lisäksi myös suuri lääketieteellinen ja kansantervydellinen merkitys.

Publications and other outputs

1 of 22

Computational thermochemistry : extension of Benson group additivity approach to organoboron compounds and reliable predictions of their thermochemical properties (2022) Vuori, Hannu T.; et al.; A1; OA
High-Level Ab Initio Predictions of Thermochemical Properties of Organosilicon Species : Critical Evaluation of Experimental Data and a Reliable Benchmark Database for Extending Group Additivity Approaches (2022) Vuori, Hannu T.; et al.; A1; OA
Multinuclear and Solid State NMR of Gels (2020) Nonappa; et al.; A3; OA; 978-1-78801-317-8
Benson group additivity values of phosphines and phosphine oxides : Fast and accurate computational thermochemistry of organophosphorus species (2019) Vuori, Hannu; et al.; A1; OA
Conformational and Tautomeric Control by Supramolecular Approach in Ureido-N-iso-propyl,N’-4-(3-pyridin-2-one)pyrimidine (2019) Kwiatkowski, Adam; et al.; A1; OA
On the carrier of inertia (2018) Grahn, Patrick; et al.; A1; OA
NMR Spectroscopy, Heteronuclei, Y-Cd (2017) Kolehmainen, Erkki; B2
Spectral and microscopic study of self-assembly of novel cationic spermine amides of betulinic acid (2017) Bildziukevich, Uladzimir; et al.; A1
Synthesis and structural studies on Ni(II) dithiocarbamates : Exploring intramolecular Ni···H-C interactions (2017) Prakasam, Balasubramaniam Arul; et al.; A1; OA
Atomism Revisited (2016) Annila, Arto; et al.; A1; OA
Caffeine as a Gelator (2016) Nonappa, Nonappa; et al.; A1; OA
Multifunctional Bile Acid Derivatives as Efficient RNA Transporters (Carriers) (2016) Král, Vladimir; et al.; A1
On the exhaust of electromagnetic drive (2016) Grahn, Patrick; et al.; A1; OA
Solid state NMR studies of gels derived from low molecular mass gelators (2016) Nonappa, Nonappa; et al.; A2
Synthesis, NMR spectral and structural studies on mixed ligand complexes of Pd(II) dithiocarbamates: First structural report on palladium(II) dithiocarbamate with SCN-ligand (2016) Prakasam, Balasubramaniam Arul; et al.; A1