Jaakko Hentilä

ORCID link: https://orcid.org/0000-0001-8211-8827

No active affiliation

Research interests

In my PhD thesis, I study the effects of exercise, muscle growth, muscle wasting and muscle wasting blocking on protein homeostasis in skeletal muscle. My thesis will provide new information about muscle physiology in muscle growth and wasting, which may be utilized to treat muscle wasting.

Fields of science

315 Sport and fitness sciences (Medical and Health sciences)

Follow-up groups

Exercise Physiology (Faculty of Sport and Health Sciences LTK, SPORT) LFY

Personal keywords

Unfolded protein response, muscle wasting, muscle hypertrophy, exercise

Publications and other outputs

Muscle follistatin gene delivery increases muscle protein synthesis independent of periodical physical inactivity and fasting (2021) Nissinen, Tuuli A.; et al.; A1; OA
Muscle NAD+ depletion and Serpina3n as molecular determinants of murine cancer cachexia : the effects of blocking myostatin and activins (2020) Hulmi, J.; et al.; A1; OA
Muscle physiology and proteostasis : effects of changes in muscle size and exercise (2020) Hentilä, Jaakko; G5; OA; 978-951-39-8120-4
Sprint and Strength Training Modulates Autophagy and Proteostasis in Aging Sprinters (2020) Hentilä, Jaakko; et al.; A1; OA
Activin Receptor Ligand Blocking and Cancer Have Distinct Effects on Protein and Redox Homeostasis in Skeletal Muscle and Liver (2019) Hentilä, Jaakko; et al.; A1; OA
Blocking Activin Receptor Ligands Is Not Sufficient to Rescue Cancer-Associated Gut Microbiota : A Role for Gut Microbial Flagellin in Colorectal Cancer and Cachexia? (2019) Pekkala, Satu; et al.; A1; OA
Muscle and serum metabolomes are dysregulated in colon-26 tumor-bearing mice despite amelioration of cachexia with activin receptor type 2B ligand blockade (2019) Lautaoja, Juulia; et al.; A1; OA
Autophagy is induced by resistance exercise in young men but unfolded protein response is induced regardless of age (2018) Hentilä, Jaakko; et al.; A1; OA
Treating cachexia using soluble ACVR2B improves survival, alters mTOR localization, and attenuates liver and spleen responses (2018) Nissinen, Tuuli; et al.; A1; OA
Opetustapahtuman ohjaaminen: ohjeet, näytöt ja palautteen antaminen (2017) Hentilä, Jaakko; et al.; B2
Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress (2016) Hulmi, Juha; et al.; A1; OA