Ulla Pentikäinen

ORCID link: https://orcid.org/0000-0001-6547-1282

No active affiliation

Research interests

In many diseases fundamental cellular processes, such as cells ability to sense and respond to mechanical forces of their environment, are disturbed. Our aim is to understand how signal transduction functions at protein level and how force transmission is altered in various diseases.

Follow-up groups

Cell and Molecular Biology (Department of Biological and Environmental Science BIOENV) SMB

Projects as Principal investigator

Filamiinien fysiologisten ominaisuuksien
- Research Council of Finland
01/09/2014-31/08/2017
The regulation mecjanisms of filamins' physiological functions
- Research Council of Finland
01/09/2014-31/12/2017

Publications and other outputs

Critical Structural Defects Explain Filamin A Mutations Causing Mitral Valve Dysplasia (2019) Haataja, Tatu J.K.; et al.; A1; OA
Non-syndromic Mitral Valve Dysplasia Mutation Changes the Force Resilience and Interaction of Human Filamin A (2019) Haataja, Tatu; et al.; A1; OA
Structural and Functional Insights into Lysostaphin-Substrate Interaction (2018) Tossavainen, Helena; et al.; A1; OA
Skeletal Dysplasia Mutations Effect on Human Filamins’ Structure and Mechanosensing (2017) Seppälä, Jonne; et al.; A1; OA
Flexible Structure of Peptide-Bound Filamin A Mechanosensor Domain Pair 20–21 (2015) Seppälä, Jonne; et al.; A1; OA
A Novel Structural Unit in the N-terminal Region of Filamins (2014) Sethi, Ritika; et al.; A1
Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone. (2013) Ylilauri, Mikko; et al.; A1
The C-terminal rod 2 fragment of filamin A forms a compact structure that can be extended (2012) Ruskamo, Salla; et al.; A1; OA
Assembly of a filamin four-domain fragment and the influence of splicing variant-1 on the structure. (2011) Pentikäinen, Ulla; et al.; A1
Novel Hydrazine Molecules as Tools To Understand the Flexibility of Vascular Adhesion Protein-1 Ligand-Binding Site: Toward More Selective Inhibitors (2011) Nurminen, Elisa; et al.; A1
Synthesis, in Vitro Activity, and Three-Dimensional Quantitative Structure-Activity Relationship of Novel Hydrazine Inhibitors of Human Vascular Adhesion Protein-1 (2010) Nurminen, Elisa; et al.; A1
Lennard-Jones Parameters for B3LYP/CHARMM27 (2009) Pentikäinen, Ulla; et al.; A1
The regulation mechanism for the auto-inhibition of binding of human filamin A to integrin (2009) Pentikäinen, Ulla; et al.; A1
Cooperative symmetric to asymmetric conformational transition of the apo-form of scavenger decapping enzyme revealed by simulations (2008) Pentikäinen, Ulla; et al.; A1