Innovative sensor Devices for the ENanTIoselective detection of CHIral Pollutants (INITIO)
Päärahoittaja
Rahoittajan antama koodi/diaarinumero: 828779
Päärahoittajan myöntämä tuki (€)
- 228 750,00
Rahoitusohjelma
Hankkeen aikataulu
Hankkeen aloituspäivämäärä: 01.01.2019
Hankkeen päättymispäivämäärä: 30.06.2022
Tiivistelmä
Chiral pollution is becoming an important topic, considering that a large number of chemicals spread into the environment, for example pesticides, are chiral substances. However, usually the stereoisomerism of contaminants is not considered, although the biological activity of enantiomers is significantly different, making their recognition critical for environmental control.
Enantiomeric excess is currently determined by off-site analysis, which requires collection, transportation, eventual pre-treating of the sample, and expensive instrumentations and specifically trained staff. Thus, providing devices able to allow rapid on site detection and chiral discrimination of target analytes would have a dramatic impact in all the fields of environmental control with significant economic benefits.
The development of chemical sensors has been conceived to bypass restrictions related to classical analytical protocols and supports the use of conventional laboratory techniques for environmental control. While the technological foundation for chemical sensors already exists, it has been difficult to apply them to chiral discrimination and analyse, due to the lack of suitable solid state receptors.
The main aims of the project are: a) the development of novel molecular receptors, based on porphyrin derivatives, b) integration of the receptors with different nanostructures and characterization their solid state organization, c) deposition of the structures onto transducer surfaces, d) testing and validation of the new chemical sensor devices with enantiomeric pairs of model analytes.
The synergistic complementary know-how of six academic units and two companies will allow a breakthrough development through delivery of sensing devices ranging from the synthesis of macrocyclic molecular receptors to the building of the analytical and electronic parts of the final, field-capable device.
Enantiomeric excess is currently determined by off-site analysis, which requires collection, transportation, eventual pre-treating of the sample, and expensive instrumentations and specifically trained staff. Thus, providing devices able to allow rapid on site detection and chiral discrimination of target analytes would have a dramatic impact in all the fields of environmental control with significant economic benefits.
The development of chemical sensors has been conceived to bypass restrictions related to classical analytical protocols and supports the use of conventional laboratory techniques for environmental control. While the technological foundation for chemical sensors already exists, it has been difficult to apply them to chiral discrimination and analyse, due to the lack of suitable solid state receptors.
The main aims of the project are: a) the development of novel molecular receptors, based on porphyrin derivatives, b) integration of the receptors with different nanostructures and characterization their solid state organization, c) deposition of the structures onto transducer surfaces, d) testing and validation of the new chemical sensor devices with enantiomeric pairs of model analytes.
The synergistic complementary know-how of six academic units and two companies will allow a breakthrough development through delivery of sensing devices ranging from the synthesis of macrocyclic molecular receptors to the building of the analytical and electronic parts of the final, field-capable device.
Vastuullinen johtaja
Muut hankkeeseen liittyvät henkilöt (JYU)
Päävastuullinen yksikkö
Seurantakohteet
Profiloitumisalue: Nanoscience Center (Fysiikan laitos PHYS, JYFL) (Matemaattis-luonnontieteellinen tiedekunta) (Kemian laitos CHEM) (Bio- ja ympäristötieteiden laitos BIOENV) NSC
Liittyvät julkaisut ja muut tuotokset
- Supramolecular Chirogenesis in Bis-Porphyrin : Crystallographic Structure and CD Spectra for a Complex with a Chiral Guanidine Derivative (2021) Osadchuk, Irina; et al.; A1; OA
- Thiourea Organocatalysts as Emerging Chiral Pollutants : En Route to Porphyrin-Based (Chir)Optical Sensing (2021) Konrad, Nele; et al.; A1; OA
- Formation and trapping of the thermodynamically unfavoured inverted-hemicucurbit[6]uril (2019) Prigorchenko, Elena; et al.; A1; OA
