Exercise, Extracellular vesicles and Senescence (EEVaS)
Molecular mechanisms promoting healthspan
 (EEVaS)


Main funder

Funder's project number354603


Funds granted by main funder (€)

  • 702 781,00


Funding program


Project timetable

Project start date01/09/2023

Project end date31/08/2027


Summary

Age is the main risk factor for the prevalent chronic diseases of developed countries. This fact has raised the question whether we should treat aging instead of treating individual diseases. Accumulation of senescent cells with age underlie several chronic diseases, whereas exercise diminishes the markers of cellular senescence. The biological significance of cellular senescence on healthy aging remains yet to be fully understood. Exercise, Extracellular vesicles and Senescence - Molecular mechanisms promoting healthspan (EEVaS) study aims to establish the key signaling molecules mediating the senolytic effects of exercise. To reveal the mechanisms, EEVaS study utilizes cell, animal, and human models. The study will be carried out at the Gerontology Research Center, Faculty of Sport and Health Sciences, University of Jyväskylä, Finland. When successful, the results of EEVaS study have potential to be translational to human health in delaying the onset of age-related chronic diseases and hence, increasing healthspan.


Principal Investigator


Primary responsible unit


Follow-up groups

Profiling areaBehaviour change, health, and well-being across the lifespan (University of Jyväskylä JYU) BC-WellSchool of Wellbeing (University of Jyväskylä JYU) JYU.Well


Related publications and other outputs


Last updated on 2024-17-04 at 13:02