Adequate muscle mass and aerobic capacity prolonging survival from muscle wasting (expenses for the last 2 years) (MassA)


Main funder


Funds granted by main funder (€)

219 998,00


Funding program

Research costs of Academy Research Fellow, AoF (Academy of Finland)


Project timetable

Project start date: 01/09/2017

Project end date: 31/08/2019


Summary

Skeletal muscle wasting and decreased aerobic capacity occur in aging and in many diseases and injuries. These changes in muscle are associated with high mortality and decreased quality of life. This study investigates the importance of muscle mass and muscle aerobic capacity alone or in combination on survival from terminal muscle wasting (cachexia) stimuli. This is accomplished by using various experimental models of cancer cachexia achieving the possibility to understand the causality. As a translational approach, the study plan also includes two large human research cohorts.

It is the goal of the study to better understand muscle wasting and the importance of good physical shape of an individual. In other words, why muscle affords health protection in disease?


Principal Investigator


Primary responsible unit


Last updated on 2019-10-10 at 10:35