Hippocampal oscillations and associative learning: Stepping out of the maze and
exploring new waves (research costs)


Main funder

Funder's project number: 313334


Funds granted by main funder (€)

  • 6 160,00


Funding program


Project timetable

Project start date: 01/09/2017

Project end date: 31/12/2019


Summary

Hippocampus is undoubtedly the brain structure most involved in learning and memory. Yet, research has been focused on only a limited set of phenomena: It is currently hypothesized that hippocampal oscillations called theta (~6 Hz) are responsible for encoding information whereas ripples (~200 Hz) are the means of long-term memory consolidation. However, evidence is limited and contradictory. Here, the role of both hippocampal theta and ripples in learning are investigated using a model of associative learning called eyeblink classical conditioning. In addition, the role of hippocampal dentate spikes, a phenomenon overlooked for the past 15 years, is examined. The aim is to identify moments in time when the brain most efficiently encodes information as well as to elucidate the systems level mechanisms of memory consolidation. Eventually, the results obtained can be tested in humans and ultimately applied
to optimize learning in both healthy and diseased brains.


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Last updated on 2021-17-03 at 12:06