A2 Review article, Literature review, Systematic review
The Effect of a Ketogenic Low-Carbohydrate, High-Fat Diet on Aerobic Capacity and Exercise Performance in Endurance Athletes : A Systematic Review and Meta-Analysis (2021)


Cao, J., Lei, S., Wang, X., & Cheng, S. (2021). The Effect of a Ketogenic Low-Carbohydrate, High-Fat Diet on Aerobic Capacity and Exercise Performance in Endurance Athletes : A Systematic Review and Meta-Analysis. Nutrients, 13(8), Article 2896. https://doi.org/10.3390/nu13082896


JYU authors or editors


Publication details

All authors or editorsCao, Jingguo; Lei, Siman; Wang, Xiuqiang; Cheng, Sulin

Journal or seriesNutrients

eISSN2072-6643

Publication year2021

Publication date23/08/2021

Volume13

Issue number8

Article number2896

PublisherMDPI AG

Publication countrySwitzerland

Publication languageEnglish

DOIhttps://doi.org/10.3390/nu13082896

Publication open accessOpenly available

Publication channel open accessOpen Access channel

Publication is parallel published (JYX)https://jyx.jyu.fi/handle/123456789/77640


Abstract

A low-carbohydrate, high-fat (LCHF) diet has been proposed to enhance the fat utilization of muscle and the aerobic capacity of endurance athletes, thereby improving their exercise performance. However, it remains uncertain how the macronutrient intake shift from carbohydrate to fat affects endurance exercise training and performance. This study performed a systematic review and meta-analysis to explore the effects of a ketogenic low-carbohydrate, high-fat (K-LCHF) diet on aerobic capacity and exercise performance among endurance athletes. Searches were carried out in five electronic databases, and we followed the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines. The search included studies using an LCHF diet as an intervention protocol and compared data on factors such as maximum oxygen uptake (VO2max) and rating of perceived exertion (RPE) from the graded exercise test. In this case, 10 studies met the criteria and were included in the meta-analysis. We did not find a significant effect of K-LCHF diet interventions on VO2max, time to exhaustion, HRmax or RPE. However, a significant overall effect in the substrate oxidation response to respiratory exchange rate was observed. The meta-analysis showed that K-LCHF diets did not affect aerobic capacity and exercise performance. Therefore, high-quality interventions of a K-LCHF diet are needed to illustrate its effect on various endurance training programs.


Keywordsketogenic dietaerobic capacityendurance sportssystematic reviewsmeta-analysis

Free keywordsketogenic low-carbohydrate; high-fat diet; endurance athletes


Contributing organizations


Ministry reportingYes

Reporting Year2021

JUFO rating1


Last updated on 2024-03-04 at 19:56