A1 Journal article (refereed)
Association between cardiorespiratory fitness and metabolic health in overweight and obese adults (2022)


Haapala, E. A., Sjöros, T., Laine, S., Garthwaite, T., Kallio, P., Saarenhovi, M., Vähä-Ypyä, H., Löyttyniemi, E., Sievänen, H., Houttu, N., Laitinen, K., Kalliokoski, K., Knuuti, J., Vasankari, T., & Heinonen, I. H. A. (2022). Association between cardiorespiratory fitness and metabolic health in overweight and obese adults. Journal of Sports Medicine and Physical Fitness, 62(11), 1526-1533. https://doi.org/10.23736/S0022-4707.21.13234-7


JYU authors or editors


Publication details

All authors or editors: Haapala, Eero A.; Sjöros, Tanja; Laine, Saara; Garthwaite, Taru; Kallio, Petri; Saarenhovi, Maria; Vähä-Ypyä, Henri; Löyttyniemi, Eliisa; Sievänen, Harri; Houttu, Noora; et al.

Journal or series: Journal of Sports Medicine and Physical Fitness

ISSN: 0022-4707

eISSN: 1827-1928

Publication year: 2022

Volume: 62

Issue number: 11

Pages range: 1526-1533

Publisher: Edizioni Minerva Medica

Publication country: Italy

Publication language: English

DOI: https://doi.org/10.23736/S0022-4707.21.13234-7

Publication open access: Not open

Publication channel open access: 

Publication is parallel published (JYX): https://jyx.jyu.fi/handle/123456789/79981


Abstract

BACKGROUND: Cardiorespiratory fitness (CRF) has been inversely associated with insulin resistance and clustering of cardiometabolic risk factors among overweight and obese individuals. However, most previous studies have scaled CRF by body mass (BM) possibly inflating the association between CRF and cardiometabolic health. We investigated the associations of peak oxygen uptake (V̇ O2peak) and peak power output (Wpeak) scaled either by BM-1, fat free mass (FFM-1), or by allometric methods with individual cardiometabolic risk factors and clustering of cardiometabolic risk factors in 55 overweight or obese adults with metabolic syndrome.
METHODS: V̇ O2peak and Wpeak were assessed by a maximal cycle ergometer exercise test. FFM was measured by air displacement plethysmograph and glucose, insulin, HbA1c, triglycerides, and total, LDL, and HDL cholesterol from fasting blood samples. HOMA-IR and metabolic syndrome score (MetS) were computed.
RESULTS: V̇ O2peak and Wpeak scaled by BM-1 were inversely associated with insulin (β=-0.404 to -0.372, 95% CI=-0.704 to -0.048), HOMA-IR (β=-0.442 to -0.440, 95% CI=-0.762 to -0.117), and MetS (β=-0.474 to -0.463, 95% CI’s=-0.798 to -0.127). Other measures of CRF were not associated with cardiometabolic risk factors.
CONCLUSIONS: Our results suggest that using BM-1 as a scaling factor confounds the associations between CRF and cardiometabolic risk in overweight/obese adults with the metabolic syndrome.


Keywords: physical fitness; aerobic capacity; metabolic syndrome; insulin resistance; overweight; obesity

Free keywords: aerobic fitness; metabolic syndrome; insulin resistance; allometry


Contributing organizations


Ministry reporting: Yes

Reporting Year: 2022

JUFO rating: 1


Last updated on 2024-03-04 at 18:06