A2 Review article, Literature review, Systematic review
Early Life Influences on Hearing in Adulthood : a Systematic Review and Two-Step Individual Patient Data Meta-Analysis (2022)
Dawes, P., Newall, J., Graham, P. L., Osmond, C., von Bonsdorff, M. B., & Eriksson, J. G. (2022). Early Life Influences on Hearing in Adulthood : a Systematic Review and Two-Step Individual Patient Data Meta-Analysis. Ear and Hearing, 43(3), 722-732. https://doi.org/10.1097/AUD.0000000000001163
JYU authors or editors
Publication details
All authors or editors: Dawes, Piers; Newall, John; Graham, Petra L.; Osmond, Clive; von Bonsdorff, Mikaela B.; Eriksson, Johan Gunnar
Journal or series: Ear and Hearing
ISSN: 0196-0202
eISSN: 1538-4667
Publication year: 2022
Publication date: 08/12/2021
Volume: 43
Issue number: 3
Pages range: 722-732
Publisher: Lippincott Williams & Wilkins
Publication country: United States
Publication language: English
DOI: https://doi.org/10.1097/AUD.0000000000001163
Publication open access: Openly available
Publication channel open access: Partially open access channel
Publication is parallel published (JYX): https://jyx.jyu.fi/handle/123456789/79288
Abstract
Adverse prenatal and early childhood development may increase susceptibility of hearing loss in adulthood. The objective was to assess whether indices of early development are associated with adult-onset hearing loss in adults ≥18 years.
Design:
In a systematic review and meta-analysis, four electronic databases were searched for studies reporting associations between indices of early development (birth weight and adult height) and adult-onset hearing loss in adults ≥18 years. We screened studies, extracted data, and assessed risk of bias. Authors were contacted to provide adjusted odds ratios from a logistic regression model for relationships between birth weight/adult height and normal/impaired hearing enabling a two-step individual patient data random-effects meta-analysis to be carried out. The study is registered with PROSPERO, CRD42020152214.
Results:
Four studies of birth weight and seven of adult height were identified. Three studies reported smaller birth weight associated with poorer adult hearing. Six studies reported shorter height associated with poorer hearing. Risk of bias was low to moderate. Four studies provided data for two-step individual patient data random-effects meta-analysis. Odds of hearing impairment were 13.5% lower for every 1 kg increase in birth weight [OR: 0.865 (95% confidence interval: 0.824 to 0.909)] in adulthood over two studies (N=81,289). Every 1 cm increase in height was associated with a 3% reduction in the odds of hearing impairment [OR: 0.970 (95% confidence interval: 0.968 to 0.971)] over four studies (N=156,740).
Conclusions:
Emerging evidence suggests that adverse early development increases the likelihood of hearing impairment in adulthood. Research and public health attention should focus on the potential for prevention of hearing impairment by optimizing development in early life.
Keywords: physical development; birth weight; height growth; hearing loss; systematic reviews; meta-analysis
Contributing organizations
Ministry reporting: Yes
Reporting Year: 2022
JUFO rating: 2
