A1 Journal article (refereed)
Synthesis of nanostructured protein–mineral-microcapsules by sonication (2022)


Doering, U., Grigoriev, D., Tapio, K., Bald, I., & Böker, A. (2022). Synthesis of nanostructured protein–mineral-microcapsules by sonication. Soft Matter, 18(13), 2558-2568. https://doi.org/10.1039/D1SM01638E


JYU authors or editors


Publication details

All authors or editorsDoering, Ulrike; Grigoriev, Dmitry; Tapio, Kosti; Bald, Ilko; Böker, Alexander

Journal or seriesSoft Matter

ISSN1744-683X

eISSN1744-6848

Publication year2022

Volume18

Issue number13

Pages range2558-2568

PublisherRoyal Society of Chemistry (RSC)

Publication countryUnited Kingdom

Publication languageEnglish

DOIhttps://doi.org/10.1039/D1SM01638E

Publication open accessOpenly available

Publication channel open accessPartially open access channel

Publication is parallel published (JYX)https://jyx.jyu.fi/handle/123456789/80393


Abstract

We propose a simple and eco-friendly method for the formation of composite protein–mineral-microcapsules induced by ultrasound treatment. Protein- and nanoparticle-stabilized oil-in-water (O/W) emulsions loaded with different oils are prepared using high-intensity ultrasound. The formation of thin composite mineral proteinaceous shells is realized with various types of nanoparticles, which are pre-modified with Bovine Serum Albumin (BSA) and subsequently characterized by EDX, TGA, zeta potential measurements and Raman spectroscopy. Cryo-SEM and EDX mapping visualizations show the homogeneous distribution of the densely packed nanoparticles in the capsule shell. In contrast to the results reported in our previous paper,1 the shell of those nanostructured composite microcapsules is not cross-linked by the intermolecular disulfide bonds between BSA molecules. Instead, a Pickering-Emulsion formation takes place because of the amphiphilicity-driven spontaneous attachment of the BSA-modified nanoparticles at the oil/water interface. Using colloidal particles for the formation of the shell of the microcapsules, in our case silica, hydroxyapatite and calcium carbonate nanoparticles, is promising for the creation of new functional materials. The nanoparticulate building blocks of the composite shell with different chemical, physical or morphological properties can contribute to additional, sometimes even multiple, features of the resulting capsules. Microcapsules with shells of densely packed nanoparticles could find interesting applications in pharmaceutical science, cosmetics or in food technology.


Keywordsnanoparticlesproteinsmineralsemulsionsultrasoundnanotechnologymicrotechnologycapsulesfunctional materials


Contributing organizations


Ministry reportingYes

VIRTA submission year2022

JUFO rating2


Last updated on 2024-12-10 at 12:45