A1 Journal article (refereed)
Synthesis, X-ray structure, Hirshfeld, and antimicrobial studies of new Ag(I) complexes based on pyridine-type ligands (2022)

El-Naggar, M. A., Abu-Youssef, M. A., Soliman, S. M., Haukka, M., Al-Majid, A. M., Barakat, A., & Badr, A. M. (2022). Synthesis, X-ray structure, Hirshfeld, and antimicrobial studies of new Ag(I) complexes based on pyridine-type ligands. Journal of Molecular Structure, 1264, Article 133210. https://doi.org/10.1016/j.molstruc.2022.133210

JYU authors or editors

Publication details

All authors or editors: El-Naggar, Mostafa A.; Abu-Youssef, Morsy A.M.; Soliman, Saied M.; Haukka, Matti; Al-Majid, Abdullah Mohammed; Barakat, Assem; Badr, Ahmed M.A.

Journal or series: Journal of Molecular Structure

ISSN: 0022-2860

eISSN: 1872-8014

Publication year: 2022

Publication date: 03/05/2022

Volume: 1264

Article number: 133210

Publisher: Elsevier

Publication country: Netherlands

Publication language: English

DOI: https://doi.org/10.1016/j.molstruc.2022.133210

Publication open access: Not open

Publication channel open access: 

Abstract

The two silver(I) complexes [Ag(3CNPy)2(CF3COO)]n (1) and [Ag(4BzPy)2]2(CF3COO)2 (2) where 3CNPy and 4BzPy are 3-cyanopyridine and 4-benzoylpyridine, respectively, were synthesized and characterized using elemental analysis, FTIR spectra and single crystal X-ray diffraction. Complex 1 is a 1D coordination polymer through the bridging and the highly symmetric CF3COO¯ group while 2 is a dinuclear complex through strong argentophilic interaction connecting the two [Ag(4BzPy)2] cationic units. In both complexes, the pyridine ligands are acting as monodentate N-donor. Hirshfeld surface analysis revealed the importance of the polar N···H (29.9%) and H···F (10.3%) hydrogen bonds in the molecular packing of 1. For 2, the nonpolar C···H (26.2%) and the polar O···H (15.6%) interactions dominate the crystal packing. Furthermore, both complexes showed π-π stacking interactions. Antimicrobial screening revealed that 3CNPy has no activity against all tested pathogens, while 1 has good antibacterial activity. Both Ag(I) complexes and 4BzPy showed remarkable antifungal activities against A. fumigatus and C. albicans compared to Ketoconazole as control.

Keywords: coordination complexes; silver; chemical synthesis; antimicrobial compounds

Free keywords: Silver trifluoroacetate; Pyridine-type ligand; Ag(I)-Complex; Hirshfeld; Antimicrobial activity

Contributing organizations

Ministry reporting: Yes

Reporting Year: 2022

JUFO rating: 1