A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Reliable fluorescence technique to detect the antibiotic colistin, a possible environmental threat due to its overuse (2022)


Mandal, S., Dey Bhowmik, A., Mukhuty, A., Kundu, S., Truong, K.-N., Rissanen, K., Chattopadhyay, A., & Sahoo, P. (2022). Reliable fluorescence technique to detect the antibiotic colistin, a possible environmental threat due to its overuse. Scientific Reports, 12, Article 9307. https://doi.org/10.1038/s41598-022-13471-z


JYU-tekijät tai -toimittajat


Julkaisun tiedot

Julkaisun kaikki tekijät tai toimittajat: Mandal, Saurodeep; Dey Bhowmik, Arpan; Mukhuty, Alpana; Kundu, Shampa; Truong, Khai-Nghi; Rissanen, Kari; Chattopadhyay, Ansuman; Sahoo, Prithidipa

Lehti tai sarja: Scientific Reports

eISSN: 2045-2322

Julkaisuvuosi: 2022

Ilmestymispäivä: 03.06.2022

Volyymi: 12

Artikkelinumero: 9307

Kustantaja: Nature Publishing Group

Julkaisumaa: Britannia

Julkaisun kieli: englanti

DOI: https://doi.org/10.1038/s41598-022-13471-z

Julkaisun avoin saatavuus: Avoimesti saatavilla

Julkaisukanavan avoin saatavuus: Kokonaan avoin julkaisukanava

Julkaisu on rinnakkaistallennettu (JYX): https://jyx.jyu.fi/handle/123456789/82018


Tiivistelmä

Colistin, considered a drug of last resort as it is effective towards multidrug-resistant Gram-negative bacterial infections. Oral administration of colistin in the poultry industry is a common practice, not only to prevent and reduce bacterial infections, but also as a rapid-growth promoter. Long-term exposure to any antibiotic will eventually lead to the development of bacterial resistance towards all antibiotics through various mechanisms in the physiological system and environment. Chicken is the most consumed source of animal protein for humans throughout the world. In addition, the manure of poultry, containing traces of the used antibiotics, is being used in farming. Exposure to excess amounts of colistin causes a great concern not only to the humans but to the environment as a whole. In the present contribution, colistin has been detected in chicken hepatocyte cells through in vivo confocal microscopy. In addition, the amount of colistin in the chicken excrements has been estimated. A simple chemosensor NAF, a dye-based on napthaldehyde furfural, was developed for the detection of colistin, supplemented with experimental evidence and theoretical calculations.


YSO-asiasanat: ympäristökemia; haitalliset aineet; antibiootit; heterosykliset yhdisteet; fluoresenssi


Liittyvät organisaatiot

JYU-yksiköt:


OKM-raportointi: Kyllä

Raportointivuosi: 2022

Alustava JUFO-taso: 1


Viimeisin päivitys 2022-20-09 klo 14:59