A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Reliable fluorescence technique to detect the antibiotic colistin, a possible environmental threat due to its overuse (2022)
Mandal, S., Dey Bhowmik, A., Mukhuty, A., Kundu, S., Truong, K.-N., Rissanen, K., Chattopadhyay, A., & Sahoo, P. (2022). Reliable fluorescence technique to detect the antibiotic colistin, a possible environmental threat due to its overuse. Scientific Reports, 12, Article 9307. https://doi.org/10.1038/s41598-022-13471-z
JYU-tekijät tai -toimittajat
Julkaisun tiedot
Julkaisun kaikki tekijät tai toimittajat: Mandal, Saurodeep; Dey Bhowmik, Arpan; Mukhuty, Alpana; Kundu, Shampa; Truong, Khai-Nghi; Rissanen, Kari; Chattopadhyay, Ansuman; Sahoo, Prithidipa
Lehti tai sarja: Scientific Reports
eISSN: 2045-2322
Julkaisuvuosi: 2022
Ilmestymispäivä: 03.06.2022
Volyymi: 12
Artikkelinumero: 9307
Kustantaja: Nature Publishing Group
Julkaisumaa: Britannia
Julkaisun kieli: englanti
DOI: https://doi.org/10.1038/s41598-022-13471-z
Julkaisun avoin saatavuus: Avoimesti saatavilla
Julkaisukanavan avoin saatavuus: Kokonaan avoin julkaisukanava
Julkaisu on rinnakkaistallennettu (JYX): https://jyx.jyu.fi/handle/123456789/82018
Tiivistelmä
Colistin, considered a drug of last resort as it is effective towards multidrug-resistant Gram-negative bacterial infections. Oral administration of colistin in the poultry industry is a common practice, not only to prevent and reduce bacterial infections, but also as a rapid-growth promoter. Long-term exposure to any antibiotic will eventually lead to the development of bacterial resistance towards all antibiotics through various mechanisms in the physiological system and environment. Chicken is the most consumed source of animal protein for humans throughout the world. In addition, the manure of poultry, containing traces of the used antibiotics, is being used in farming. Exposure to excess amounts of colistin causes a great concern not only to the humans but to the environment as a whole. In the present contribution, colistin has been detected in chicken hepatocyte cells through in vivo confocal microscopy. In addition, the amount of colistin in the chicken excrements has been estimated. A simple chemosensor NAF, a dye-based on napthaldehyde furfural, was developed for the detection of colistin, supplemented with experimental evidence and theoretical calculations.
YSO-asiasanat: ympäristökemia; haitalliset aineet; antibiootit; heterosykliset yhdisteet; fluoresenssi
Liittyvät organisaatiot
OKM-raportointi: Kyllä
VIRTA-lähetysvuosi: 2022
JUFO-taso: 1
