A1 Journal article (refereed)
Synthesis and characterization of a novel coordination compound based on 2, 6-dimethylpiperazine (2022)

Hannachi, A., García, C. J. G., Valkonen, A., & Smirani, W. (2022). Synthesis and characterization of a novel coordination compound based on 2, 6-dimethylpiperazine. Journal of Molecular Structure, 1267, Article 133569. https://doi.org/10.1016/j.molstruc.2022.133569

JYU authors or editors

Valkonen, Arto

Publication details

All authors or editors: Hannachi, Anissa; García, Carlos J Gómez; Valkonen, Arto; Smirani, Wajda

Journal or series: Journal of Molecular Structure

ISSN: 0022-2860

eISSN: 1872-8014

Publication year: 2022

Publication date: 24/06/2022

Volume: 1267

Article number: 133569

Publisher: Elsevier

Publication country: Netherlands

Publication language: English

DOI: https://doi.org/10.1016/j.molstruc.2022.133569

Publication open access: Not open

Publication channel open access:

Abstract

Here we show the synthesis and complete characterization, including single crystal X-ray structure determination, of the first compound containing the monoprotonated 2,6-dimethylpiperazinium cation: (C6H15N2)+. Compound [Co(NCS)4(C6H15N2)2] (1) crystallizes in the monoclinic P21/n space group and contains an octahedral Co(II) ion surrounded by four -NCS and two protonated 2,6-dimethylpiperazine ligands (C6H15N2)+. There are some N-H•••S intermolecular hydrogen bonds that generate a three-dimensional H-bonded network. Compound 1 has been characterized by single-crystal and powder X-Ray diffraction, infrared, UV-Vis and RMN spectroscopies, thermogravimetric analysis (TGA) and differential thermal analysis (DTA). The magnetic properties in the temperature range indicate the presence of isolated high spin Co(II) ions with the expected spin-orbit coupling. The antibacterial activity of compound 1 shows a higher antibacterial activity than other related complexes due to the presence of the piperazine-derivative ligands.

Keywords: cobalt; biological activity; chemical bonds; hydrogen bonds; spectroscopy

Free keywords: isothiocyanate; 2,6-dimethylpiperazine; coordination; biological activity

Fields of science: