A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Is low cardiorespiratory fitness a feature of metabolic syndrome in children and adults? (2022)
Haapala, E. A., Tompuri, T., Lintu, N., Viitasalo, A., Savonen, K., Lakka, T. A., & Laukkanen, J. A. (2022). Is low cardiorespiratory fitness a feature of metabolic syndrome in children and adults?. Journal of Science and Medicine in Sport, 25(11), 923-929. https://doi.org/10.1016/j.jsams.2022.08.002
JYU-tekijät tai -toimittajat
Julkaisun tiedot
Julkaisun kaikki tekijät tai toimittajat: Haapala, Eero A.; Tompuri, Tuomo; Lintu, Niina; Viitasalo, Anna; Savonen, Kai; Lakka, Timo A.; Laukkanen, Jari A.
Lehti tai sarja: Journal of Science and Medicine in Sport
ISSN: 1440-2440
eISSN: 1878-1861
Julkaisuvuosi: 2022
Volyymi: 25
Lehden numero: 11
Artikkelin sivunumerot: 923-929
Kustantaja: Elsevier
Julkaisumaa: Alankomaat
Julkaisun kieli: englanti
DOI: https://doi.org/10.1016/j.jsams.2022.08.002
Julkaisun avoin saatavuus: Avoimesti saatavilla
Julkaisukanavan avoin saatavuus: Osittain avoin julkaisukanava
Julkaisu on rinnakkaistallennettu (JYX): https://jyx.jyu.fi/handle/123456789/83836
Tiivistelmä
Cardiorespiratory fitness (CRF) has been inversely associated with risk of cardiometabolic diseases. However, there are no studies comparing the independent associations of CRF scaled by body size and composition using different approaches with cardiometabolic risk factors between children and adults. We therefore investigated these associations in children and adults using same measures for CRF and cardiometabolic risk factors.
Design
Cross-sectional.
Methods
A total of 352 children (47.2 % girls) and 572 men were included in the study. Peak oxygen uptake (V̇O2peak) was measured during a maximal exercise test on a cycle ergometer and was scaled by total body mass (BM−1), total fat free mass (FFM−1), and allometrically modelled BM, FFM, and stature. Insulin, glucose, triglycerides, HDL cholesterol, and LDL cholesterol were assessed from fasting blood samples and systolic and diastolic blood pressure were measured. HOMA-IR and continuous metabolic risk score were computed.
Results
V̇O2peak scaled by BM−1 was inversely associated with insulin, HOMA-IR, triglycerides, diastolic blood pressure, the cardiometabolic risk score and the number of cardiometabolic risk factors in children and adults. However, these associations attenuated remarkably when V̇O2peak was scaled by total FFM or allometrically modelled BM, FFM, or stature. V̇O2peak was consistently and positively associated with HDL cholesterol in children and adults irrespective of the scaling approach.
Conclusions
The inverse associations of CRF with cardiometabolic risk factors among children and adults attenuated remarkably when body size and composition were appropriately controlled for. However, the positive association between CRF and HDL cholesterol was consistent irrespective of the scaling approach.
YSO-asiasanat: aineenvaihduntahäiriöt; metabolinen oireyhtymä; riskitekijät; lapset (ikäryhmät); aikuiset; lihavuus; ylipaino; kunto; kehonkoostumus; insuliiniresistenssi; kolesteroli; LDL-kolesteroli; HDL-kolesteroli; mittausmenetelmät; ennaltaehkäisy; terveysvaikutukset; lastentautioppi
Vapaat asiasanat: fitness; metabolic syndrome; insulin resistance; paediatrics; obesity; body composition
Liittyvät organisaatiot
Hankkeet, joissa julkaisu on tehty
- Lasten ja nuorten liikunnan ravitsemuksen merkitys aivojen terveydelle
- Haapala, Eero
- Juho Vainion Säätiö
OKM-raportointi: Kyllä
Raportointivuosi: 2022
JUFO-taso: 2
