A1 Journal article (refereed)
Changes in the Severity of Frailty Among Older Adults After 12 Months of Supervised Home-Based Physical Exercise : A Randomized Clinical Trial (2022)

Suikkanen, S., Soukkio, P., Kautiainen, H., Kääriä, S., Hupli, M. T., Sipilä, S., Pitkälä, K., Aartolahti, E., & Kukkonen-Harjula, K. (2022). Changes in the Severity of Frailty Among Older Adults After 12 Months of Supervised Home-Based Physical Exercise : A Randomized Clinical Trial. Journal of the American Medical Directors Association, 23(10), 1717.e9-1717.e15. https://doi.org/10.1016/j.jamda.2022.07.010

JYU authors or editors

Publication details

All authors or editorsSuikkanen, Sara; Soukkio, Paula; Kautiainen, Hannu; Kääriä, Sanna; Hupli, Markku T.; Sipilä, Sarianna; Pitkälä, Kaisu; Aartolahti, Eeva; Kukkonen-Harjula, Katriina

Journal or seriesJournal of the American Medical Directors Association



Publication year2022


Issue number10

Pages range1717.e9-1717.e15

PublisherElsevier BV

Publication countryUnited States

Publication languageEnglish


Publication open accessNot open

Publication channel open accessChannel is not openly available

Publication is parallel published (JYX)https://jyx.jyu.fi/handle/123456789/86169


To investigate the effects of 12 months of physiotherapist-supervised, home-based physical exercise on the severity of frailty and on the prevalence of the 5 frailty phenotype criteria, using secondary analyses.

Randomized clinical trial, with 1:1 allocation into 12-month home-based physical exercise, or usual care. The multicomponent exercise sessions (60 minutes) were supervised by the physiotherapist and included strength, balance, functional, and flexibility exercises twice a week at participants' homes.

Setting and Participants
Home-dwelling older adults aged ≥65 years who were frail (meeting 3-5 criteria) or prefrail (1-2 criteria) according to frailty phenotype criteria.

The severity of frailty (nonfrail, prefrail, or frail) was assessed using frailty phenotype criteria, and the prevalence of each frailty criterion (weight loss, low physical activity, exhaustion, weakness, and slowness) were assessed at baseline and at 12 months.

Two hundred ninety-nine persons were included in the analyses, of whom 184 were prefrail and 115 were frail at baseline. Their mean age was 82.5 (SD 6.3) years, and 75% were women. There was a significant difference between the exercise and usual care groups' transitions to different frailty states from baseline to 12 months among those who at baseline were prefrail (P = .032) and frail (P = .009). At 12 months, the mean number of frailty criteria had decreased in the exercise group (−0.27, 95% CI –0.47, −0.08) and remained unchanged in the usual care group (0.01, 95% CI –0.16, 0.18; P = .042). The prevalence of the exhaustion (P = .009) and the low physical activity (P < .001) criteria were lower at 12 months in the exercise group than in the usual care group.

Conclusions and Implications
The severity of frailty can be reduced through 12-month supervised home-based exercise training. Exercise should be included in the care of older adults with signs of frailty.

Keywordsolder peoplefrailty syndromerehabilitationhome rehabilitationexercise therapyphysical exercisesphysical activityfunctional capacityperformance (capacity)physiotherapy

Free keywordsfrailty; older adults; physical exercise; rehabilitation

Contributing organizations

Ministry reportingYes

Reporting Year2022

JUFO rating2

Last updated on 2024-15-06 at 20:27