A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Alterations in Daphnia magna exposed to enniatin B and beauvericin provide additional value as environmental indicators (2023)
Juan-García, A., Pakkanen, H., Juan, C., & Vehniäinen, E.-R. (2023). Alterations in Daphnia magna exposed to enniatin B and beauvericin provide additional value as environmental indicators. Ecotoxicology and Environmental Safety, 249, Article 114427. https://doi.org/10.1016/j.ecoenv.2022.114427
JYU-tekijät tai -toimittajat
Julkaisun tiedot
Julkaisun kaikki tekijät tai toimittajat: Juan-García, Ana; Pakkanen, Hannu; Juan, Cristina; Vehniäinen, Eeva-Riikka
Lehti tai sarja: Ecotoxicology and Environmental Safety
ISSN: 0147-6513
eISSN: 1090-2414
Julkaisuvuosi: 2023
Volyymi: 249
Artikkelinumero: 114427
Kustantaja: Elsevier
Julkaisumaa: Yhdysvallat (USA)
Julkaisun kieli: englanti
DOI: https://doi.org/10.1016/j.ecoenv.2022.114427
Julkaisun avoin saatavuus: Avoimesti saatavilla
Julkaisukanavan avoin saatavuus: Kokonaan avoin julkaisukanava
Julkaisu on rinnakkaistallennettu (JYX): https://jyx.jyu.fi/handle/123456789/84394
Tiivistelmä
Mycotoxins beauvericin (BEA) and enniatin B (ENN B) affect negatively several systems and demand more studies as the mechanisms are still unclear. The simultaneous presence of contaminants in the environment manifests consequences of exposure for both animals and flora. Daphnia magna is considered an ideal invertebrate to detect effects of toxic compounds and environmental alterations. In this study, the potential toxicity and the basic mechanism of BEA and ENN B individually and combined were studied in D. magna. Acute and delayed toxicity were evaluated, and transcript levels of genes involved in xenobiotic metabolism (mox, gst, abcb1, and abcc5), reproduction, and oxidative stress (vtg-SOD) were analyzed by qPCR. Though no acute toxicity was found, results revealed a spinning around and circular profile of swimming, a strong decrease of survival after 72 h for BEA and ENN B at 16 µM and 6.25 µM, respectively, while for BEA + ENN B [8 + 1.6] µM after 96 h. The amount of mycotoxin remaining in the media revealed that the higher the concentration assayed the higher the amount remaining in the media. Differential regulation of genes suggests that xenobiotic metabolism is affected denoting different effects on transcription for tested mycotoxins. The results provide new insights into the underlying risk assessment of BEA and ENN B not only through food for consumers but also for the environment.
YSO-asiasanat: selkärangattomat; mykotoksiinit; ekotoksikologia
Vapaat asiasanat: invertebrates; Daphnia magna; mycotoxins; mixtures ecotoxicology
Liittyvät organisaatiot
Hankkeet, joissa julkaisu on tehty
- Fostering Outreach within European Regions, Transnational Higher Education and Mobility
- Ikonen, Mari
- Euroopan komissio
OKM-raportointi: Kyllä
VIRTA-lähetysvuosi: 2023
JUFO-taso: 2