A2 Review article, Literature review, Systematic review
Millet-inspired systems metabolic engineering of NUE in crops (2023)

Babele, P. K., Srivastava, A., Selim, K. A., & Kumar, A. (2023). Millet-inspired systems metabolic engineering of NUE in crops. Trends in Biotechnology, 41(5), 701-713. https://doi.org/10.1016/j.tibtech.2022.10.008

JYU authors or editors

Publication details

All authors or editorsBabele, Piyoosh K.; Srivastava, Amit; Selim, Khaled A.; Kumar, Anil

Journal or seriesTrends in Biotechnology



Publication year2023


Issue number5

Pages range701-713

PublisherCell Press

Publication countryUnited States

Publication languageEnglish


Publication open accessNot open

Publication channel open accessChannel is not openly available

Publication is parallel published (JYX)https://jyx.jyu.fi/handle/123456789/93732


The use of nitrogen (N) fertilizers in agriculture has a great ability to increase crop productivity. However, their excessive use has detrimental effects on the environment. Therefore, it is necessary to develop crop varieties with improved nitrogen use efficiency (NUE) that require less N but have substantial yields. Orphan crops such as millets are cultivated in limited regions and are well adapted to lower input conditions. Therefore, they serve as a rich source of beneficial traits that can be transferred into major crops to improve their NUE. This review highlights the tremendous potential of systems biology to unravel the enzymes and pathways involved in the N metabolism of millets, which can open new possibilities to generate transgenic crops with improved NUE.

Keywordsnitrogennitrogenous fertilizersenvironmental effectscultivated plantsagriculturefertilisation of plantsproductivity

Free keywordsnitrogen use efficiency; millets; flux balance analysis; metabolic flux analysis; PII protein

Contributing organizations

Ministry reportingYes

Reporting Year2023

JUFO rating2

Last updated on 2024-15-05 at 13:02