A1 Journal article (refereed)
Large-Scale Formation of DNA Origami Lattices on Silicon (2023)

Tapio, K., Kielar, C., Parikka, J. M., Keller, A., Järvinen, H., Fahmy, K., & Toppari, J. J. (2023). Large-Scale Formation of DNA Origami Lattices on Silicon. Chemistry of Materials, 35(5), 1961-1971. https://doi.org/10.1021/acs.chemmater.2c03190

JYU authors or editors

Tapio, Kosti
Parikka, Johannes
Järvinen, Heini
Toppari, Jussi

Publication details

All authors or editors: Tapio, Kosti; Kielar, Charlotte; Parikka, Johannes M.; Keller, Adrian; Järvinen, Heini; Fahmy, Karim; Toppari, J. Jussi

Journal or series: Chemistry of Materials

ISSN: 0897-4756

eISSN: 1520-5002

Publication year: 2023

Publication date: 23/02/2023

Volume: 35

Issue number: 5

Pages range: 1961-1971

Publisher: American Chemical Society (ACS)

Publication country: United States

Publication language: English

DOI: https://doi.org/10.1021/acs.chemmater.2c03190

Publication open access: Openly available

Publication channel open access: Partially open access channel

Publication is parallel published (JYX): https://jyx.jyu.fi/handle/123456789/85646

Abstract

In recent years, hierarchical nanostructures have found applications in fields like diagnostics, medicine, nano-optics, and nanoelectronics, especially in challenging applications like the creation of metasurfaces with unique optical properties. One of the promising materials to fabricate such nanostructures has been DNA due to its robust self-assembly properties and plethora of different functionalization schemes. Here, we demonstrate the assembly of a two-dimensional fishnet-type lattice on a silicon substrate using cross-shaped DNA origami as the building block, i.e., tile. The effects of different environmental and structural factors are investigated under liquid atomic force microscopy (AFM) to optimize the lattice assembly. Furthermore, the arm-to-arm binding affinity of the tiles is analyzed, revealing preferential orientations. From the liquid AFM results, we develop a methodology to produce closely-spaced DNA origami lattices on silicon substrate, which allows further nanofabrication process steps, such as metallization. This formed polycrystalline lattice has high surface coverage and is extendable to the wafer scale with an average domain size of about a micrometer. Further studies are needed to increase the domain size toward a single-crystalline large-scale lattice.

Keywords: nanostructures; DNA; silicon; atomic force microscopy

Free keywords: DNA origami; deposition; lattices; liquids; silicon

Fields of science: