A2 Review article, Literature review, Systematic review
Protein Engineering in Cyanobacterial Biotechnology : Tools and Recent Updates (2024)

Shukla, P., Tyagi, S., Kar, S., & Srivastava, A. (2024). Protein Engineering in Cyanobacterial Biotechnology : Tools and Recent Updates. Current Protein and Peptide Science, 25(2), 95-106. https://doi.org/10.2174/1389203724666230822100104

JYU authors or editors

Publication details

All authors or editorsShukla, Pratyoosh; Tyagi, Swati; Kar, Srabani; Srivastava, Amit

Journal or seriesCurrent Protein and Peptide Science



Publication year2024

Publication date22/08/2023


Issue number2

Pages range95-106

PublisherBentham Science Publishers Ltd.

Publication countryNetherlands

Publication languageEnglish


Publication open accessNot open

Publication channel open access


Cyanobacteria have emerged as a microbial cell factory to produce a variety of bioproducts, including peptides and proteins. Cyanobacteria stand out among other organisms due to their photoautotrophic metabolism and ability to produce a wide range of metabolites and proteins. As photoautotrophic hosts can produce industrial compounds and proteins by using minimal resources such as sunlight, atmospheric carbon dioxide, and fewer nutrients, cyanobacteria are cost-effective industrial hosts. Therefore, the use of protein engineering tools for rational protein design, protein motifs/domains study, and the desired modification of enzyme activity has become a desirable undertaking in cyanobacterial biology. Protein engineering can improve their biological functions as well as the stability of their intracellular proteins. This review aims to highlight the success of protein engineering in the direction of cyanobacterial biotechnology and outlines the emerging technologies, current challenges, and prospects of protein engineering in cyanobacterial biotechnology.

Keywordscyanobacteriaproteinspeptidesbiotechnologygene technology

Free keywordsCyanobacteria; protein engineering; directed evolution; site directed mutagenesis; computer-aided protein design

Contributing organizations

Ministry reportingYes

Reporting Year2023

JUFO rating1

Last updated on 2024-15-05 at 13:16