A2 Review article, Literature review, Systematic review
Protein Engineering in Cyanobacterial Biotechnology : Tools and Recent Updates (2024)
Shukla, P., Tyagi, S., Kar, S., & Srivastava, A. (2024). Protein Engineering in Cyanobacterial Biotechnology : Tools and Recent Updates. Current Protein and Peptide Science, 25(2), 95-106. https://doi.org/10.2174/1389203724666230822100104
JYU authors or editors
Publication details
All authors or editors: Shukla, Pratyoosh; Tyagi, Swati; Kar, Srabani; Srivastava, Amit
Journal or series: Current Protein and Peptide Science
ISSN: 1389-2037
eISSN: 1875-5550
Publication year: 2024
Publication date: 22/08/2023
Volume: 25
Issue number: 2
Pages range: 95-106
Publisher: Bentham Science Publishers Ltd.
Publication country: Netherlands
Publication language: English
DOI: https://doi.org/10.2174/1389203724666230822100104
Publication open access: Not open
Publication channel open access:
Abstract
Cyanobacteria have emerged as a microbial cell factory to produce a variety of bioproducts, including peptides and proteins. Cyanobacteria stand out among other organisms due to their photoautotrophic metabolism and ability to produce a wide range of metabolites and proteins. As photoautotrophic hosts can produce industrial compounds and proteins by using minimal resources such as sunlight, atmospheric carbon dioxide, and fewer nutrients, cyanobacteria are cost-effective industrial hosts. Therefore, the use of protein engineering tools for rational protein design, protein motifs/domains study, and the desired modification of enzyme activity has become a desirable undertaking in cyanobacterial biology. Protein engineering can improve their biological functions as well as the stability of their intracellular proteins. This review aims to highlight the success of protein engineering in the direction of cyanobacterial biotechnology and outlines the emerging technologies, current challenges, and prospects of protein engineering in cyanobacterial biotechnology.
Keywords: cyanobacteria; proteins; peptides; biotechnology; gene technology
Free keywords: Cyanobacteria; protein engineering; directed evolution; site directed mutagenesis; computer-aided protein design
Contributing organizations
Ministry reporting: Yes
Reporting Year: 2023
Preliminary JUFO rating: 1