A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Does sleep-disordered breathing add to impairments in academic performance and brain structure usually observed in children with overweight/obesity? (2022)


Torres-Lopez, L. V., Cadenas-Sanchez, C., Migueles, J. H., Esteban-Cornejo, I., Molina-Garcia, P., Hillman, C. H., Catena, A., & Ortega, F. B. (2022). Does sleep-disordered breathing add to impairments in academic performance and brain structure usually observed in children with overweight/obesity?. European Journal of Pediatrics, 181, 2055-2065. https://doi.org/10.1007/s00431-022-04403-0


JYU-tekijät tai -toimittajat


Julkaisun tiedot

Julkaisun kaikki tekijät tai toimittajat: Torres-Lopez, Lucia V.; Cadenas-Sanchez, Cristina; Migueles, Jairo H.; Esteban-Cornejo, Irene; Molina-Garcia, Pablo; Hillman, Charles H.; Catena, Andres; Ortega, Francisco B.

Lehti tai sarja: European Journal of Pediatrics

ISSN: 0340-6199

eISSN: 1432-1076

Julkaisuvuosi: 2022

Ilmestymispäivä: 10.02.2022

Volyymi: 181

Artikkelin sivunumerot: 2055-2065

Kustantaja: Springer

Julkaisumaa: Saksa

Julkaisun kieli: englanti

DOI: https://doi.org/10.1007/s00431-022-04403-0

Julkaisun avoin saatavuus: Avoimesti saatavilla

Julkaisukanavan avoin saatavuus: Osittain avoin julkaisukanava

Julkaisu on rinnakkaistallennettu (JYX): https://jyx.jyu.fi/handle/123456789/89624


Tiivistelmä

Approximately 4–11% of children suffer from sleep-disordered breathing (SDB), and children with obesity are at increased risk. Both obesity and SDB have been separately associated with poorer brain health, yet whether SDB severity affects brain health in children with obesity remains unanswered. This study aimed to examine associations of SDB severity with academic performance and brain structure (i.e., total brain and gray and white matter volumes and gray matter volume in the hippocampus) in children with overweight/obesity. One hundred nine children aged 8–12 years with overweight/obesity were included. SDB severity and its subscales (i.e., snoring, daytime sleepiness, and inattention/hyperactivity) were evaluated via the Pediatric Sleep Questionnaire (PSQ), and academic performance was evaluated with the Woodcock-Muñoz standardized test and school grades. Brain structure was assessed by magnetic resonance imaging. SDB severity was not associated with academic performance measured by the standardized test (all |β|> 0.160, P > 0.076), yet it was associated with the school grade point average (β = -0.226, P = 0.007) and natural and social science grades (β = -0.269, P = 0.024). Intention/hyperactivity seemed to drive these associations. No associations were found between SDB severity and the remaining school grades (all β < -0.188, P > 0.065) or brain volumes (all P > 0.05).

Conclusion: Our study shows that SDB severity was associated with lower school grades, yet it was not associated with the standardized measurement of academic performance or with brain volumes in children with overweight/obesity. SDB severity may add to academic problems in children beyond the effects contributed by overweight/obesity status alone.


YSO-asiasanat: uniapnea-oireyhtymä; uni (lepotila); hengitys; aivot; kognitio; ylipaino; lihavuus; lapset (ikäryhmät)

Vapaat asiasanat: preadolescents; childhood obesity; obstructive sleep apnea; academic achievement; brain health


Liittyvät organisaatiot


OKM-raportointi: Kyllä

VIRTA-lähetysvuosi: 2023

Alustava JUFO-taso: 1


Viimeisin päivitys 2025-12-03 klo 23:06