A1 Journal article (refereed)
Modifying the terminal phenyl group of monomethine cyanine dyes as a pathway to brighter nucleic acid probes (2024)


Alaranta, J. M., Valkonen, A. M., Shroff, S. S., Marjomäki, V. S., Rissanen, K., & Lahtinen, T. M. (2024). Modifying the terminal phenyl group of monomethine cyanine dyes as a pathway to brighter nucleic acid probes. New Journal of Chemistry, Advance Article. https://doi.org/10.1039/d3nj05400d


JYU authors or editors


Publication details

All authors or editorsAlaranta, Johanna M.; Valkonen, Arto M.; Shroff, Sailee S.; Marjomäki, Varpu S.; Rissanen, Kari; Lahtinen, Tanja M.

Journal or seriesNew Journal of Chemistry

ISSN1144-0546

eISSN1369-9261

Publication year2024

Publication date20/02/2024

VolumeAdvance Article

PublisherRoyal Society of Chemistry (RSC)

Publication countryUnited Kingdom

Publication languageEnglish

DOIhttps://doi.org/10.1039/d3nj05400d

Publication open accessOpenly available

Publication channel open accessPartially open access channel

Publication is parallel published (JYX)https://jyx.jyu.fi/handle/123456789/93826


Abstract

Three novel monomethine cyanine dyes were synthesized carrying electron donating groups to obtain
even brighter nucleic acids probes. Photophysical properties of these dyes were evaluated with DNA and
selected dyes with RNA. A great variation in brightness and binding properties of the dyes was observed.
Moreover the X-ray crystal structures are presented for two dyes.


Keywordsnucleic acidstracers (indicators)colouring agentsgene technology


Contributing organizations


Related projects


Ministry reportingYes

Reporting Year2024

Preliminary JUFO rating1


Last updated on 2024-03-07 at 20:46