A1 Journal article (refereed)
Accumulating Sedentary Time and Physical Activity From Childhood to Adolescence and Cardiac Function in Adolescence (2024)
Haapala, E. A., Leppänen, M. H., Lee, E., Savonen, K., Laukkanen, J. A., Kähönen, M., Brage, S., & Lakka, T. A. (2024). Accumulating Sedentary Time and Physical Activity From Childhood to Adolescence and Cardiac Function in Adolescence. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, 13(6), Article e031837. https://doi.org/10.1161/jaha.123.031837
JYU authors or editors
Publication details
All authors or editors: Haapala, Eero A.; Leppänen, Marja H.; Lee, Earric; Savonen, Kai; Laukkanen, Jari A.; Kähönen, Mika; Brage, Soren; Lakka, Timo A.
Journal or series: Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease
eISSN: 2047-9980
Publication year: 2024
Publication date: 19/03/2024
Volume: 13
Issue number: 6
Article number: e031837
Publisher: Wiley-Blackwell
Publication country: United States
Publication language: English
DOI: https://doi.org/10.1161/jaha.123.031837
Publication open access: Openly available
Publication channel open access: Open Access channel
Publication is parallel published (JYX): https://jyx.jyu.fi/handle/123456789/94175
Web address of parallel published publication (pre-print): https://www.medrxiv.org/content/10.1101/2023.07.19.23292912v1
Abstract
Increased physical activity (PA) may mitigate the negative cardiovascular health effects of sedentary behavior in adolescents. However, the relationship of PA and sedentary time from childhood with cardiac function in adolescence remains underexplored. Therefore, we investigated the associations of cumulative sedentary time and PA from childhood to adolescence with cardiac function in adolescence.
Methods and Results
Participants were 153 adolescents (69 girls) who were aged 6 to 8 years at baseline, 8 to 10 years at 2‐year follow‐up, and 15 to 17 years at 8‐year follow‐up. Cumulative sedentary time and PA exposure between baseline and 2‐year follow‐up and between baseline and 8‐year follow‐up were measured using a combined accelerometer and heart rate monitor. Cardiac function was assessed using impedance cardiography at 8‐year follow‐up. The data were analyzed using linear regression analyses adjusted for age and sex. Cumulative moderate to vigorous PA (standardized regression coefficient [β]=−0.323 [95% CI, −0.527 to −0.119]) and vigorous PA (β=−0.295 [95% CI, −0.508 to −0.083]) from baseline to 8‐year follow‐up were inversely associated with cardiac work at 8‐year follow‐up. Conversely, cumulative sedentary time had a positive association (β=0.245 [95% CI, 0.092−0.398]). Cumulative vigorous PA from baseline to 8‐year follow‐up was inversely associated with cardiac work index at 8‐year follow‐up (β=−0.218 [95% CI, −0.436 to 0.000]).
Conclusions
Higher levels of sedentary time and lower levels of PA during childhood were associated with higher cardiac work in adolescence, highlighting the importance of increasing PA and reducing sedentary time from childhood.
Keywords: pediatrics; heart; exercises; training; inactivity
Free keywords: exercise; heart function; pediatrics; sedentary behavior
Contributing organizations
Ministry reporting: Yes
Preliminary JUFO rating: 2
