A1 Journal article (refereed)
The associations of depressive symptoms and perceived stress with arterial health in adolescents (2024)

Toivonen, E., Lee, E., Leppänen, M. H., Laitinen, T., Kähönen, M., Lakka, T. A., & Haapala, E. A. (2024). The associations of depressive symptoms and perceived stress with arterial health in adolescents. Physiological Reports, 12(6), Article e15986. https://doi.org/10.14814/phy2.15986

JYU authors or editors

Publication details

All authors or editors: Toivonen, Emmi; Lee, Earric; Leppänen, Marja H.; Laitinen, Tomi; Kähönen, Mika; Lakka, Timo A.; Haapala, Eero A.

Journal or series: Physiological Reports

eISSN: 2051-817X

Publication year: 2024

Volume: 12

Issue number: 6

Article number: e15986

Publisher: John Wiley & Sons

Publication country: United Kingdom

Publication language: English

DOI: https://doi.org/10.14814/phy2.15986

Publication open access: Openly available

Publication channel open access: Open Access channel

Publication is parallel published (JYX): https://jyx.jyu.fi/handle/123456789/94200

Abstract

Cardiovascular and mental diseases are among the most important global health problems, but little is known on the associations between mental and arterial health in adolescents. Therefore, we investigated the associations of arterial health with depressive symptoms and perceived stress in adolescents. A total of 277 adolescents, 151 boys, 126 girls, aged 15–17 years participated in the study. Depressive symptoms were assessed using the Beck Depression Inventory and perceived stress by the Cohen Perceived Stress Scale. Arterial health was assessed by measures from carotid ultrasonography (carotid intima-media thickness, Young's Elastic Modulus, carotid artery distensibility, stiffness index), impedance cardiography (pulse wave velocity, cardio-ankle vascular index), and pulse contour analysis (reflection index, stiffness index). The data were analyzed using linear regression models adjusted for age and sex. Depressive symptoms or perceived stress were not associated with indices of arterial health in the whole study group (β = −0.08 to 0.09, p > 0.05), in boys (β = −0.13 to 0.10, p > 0.05) or in girls (standardized regression coefficient β = −0.16 to 0.08, p > 0.05). We found no associations of depressive symptoms and perceived stress with arterial health in adolescents. These observations suggest that the association between mental and arterial health problems develop in later life.

Keywords: depression (mental disorders); young people; cardiovascular diseases; stress (biological phenomena)

Free keywords: adolescent; arterial stiffness; cardiovascular risk factors; depression; perceived stress

Contributing organizations

Ministry reporting: Yes

VIRTA submission year: 2024

Preliminary JUFO rating: 1