A1 Journal article (refereed)
The associations of depressive symptoms and perceived stress with arterial health in adolescents (2024)


Toivonen, E., Lee, E., Leppänen, M. H., Laitinen, T., Kähönen, M., Lakka, T. A., & Haapala, E. A. (2024). The associations of depressive symptoms and perceived stress with arterial health in adolescents. Physiological Reports, 12(6), Article e15986. https://doi.org/10.14814/phy2.15986


JYU authors or editors


Publication details

All authors or editorsToivonen, Emmi; Lee, Earric; Leppänen, Marja H.; Laitinen, Tomi; Kähönen, Mika; Lakka, Timo A.; Haapala, Eero A.

Journal or seriesPhysiological Reports

eISSN2051-817X

Publication year2024

Volume12

Issue number6

Article numbere15986

PublisherJohn Wiley & Sons

Publication countryUnited Kingdom

Publication languageEnglish

DOIhttps://doi.org/10.14814/phy2.15986

Publication open accessOpenly available

Publication channel open accessOpen Access channel

Publication is parallel published (JYX)https://jyx.jyu.fi/handle/123456789/94200


Abstract

Cardiovascular and mental diseases are among the most important global health problems, but little is known on the associations between mental and arterial health in adolescents. Therefore, we investigated the associations of arterial health with depressive symptoms and perceived stress in adolescents. A total of 277 adolescents, 151 boys, 126 girls, aged 15–17 years participated in the study. Depressive symptoms were assessed using the Beck Depression Inventory and perceived stress by the Cohen Perceived Stress Scale. Arterial health was assessed by measures from carotid ultrasonography (carotid intima-media thickness, Young's Elastic Modulus, carotid artery distensibility, stiffness index), impedance cardiography (pulse wave velocity, cardio-ankle vascular index), and pulse contour analysis (reflection index, stiffness index). The data were analyzed using linear regression models adjusted for age and sex. Depressive symptoms or perceived stress were not associated with indices of arterial health in the whole study group (β = −0.08 to 0.09, p > 0.05), in boys (β = −0.13 to 0.10, p > 0.05) or in girls (standardized regression coefficient β = −0.16 to 0.08, p > 0.05). We found no associations of depressive symptoms and perceived stress with arterial health in adolescents. These observations suggest that the association between mental and arterial health problems develop in later life.


Keywordsdepression (mental disorders)young peoplecardiovascular diseasesstress (biological phenomena)

Free keywordsadolescent; arterial stiffness; cardiovascular risk factors; depression; perceived stress


Contributing organizations


Ministry reportingYes

Reporting Year2024

Preliminary JUFO rating1


Last updated on 2024-13-05 at 18:06