A1 Journal article (refereed)
The effect of inbreeding rate on fitness, inbreeding depression and heterosis over a range of inbreeding coefficients (2014)

Pekkala, N., Knott, E., Kotiaho, J. S., Nissinen, K., & Puurtinen, M. (2014). The effect of inbreeding rate on fitness, inbreeding depression and heterosis over a range of inbreeding coefficients. Evolutionary Applications, 7(9), 1107-1119. https://doi.org/10.1111/eva.12145

JYU authors or editors

Publication details

All authors or editorsPekkala, Nina; Knott, Emily; Kotiaho, Janne Sakari; Nissinen, Kari; Puurtinen, Mikael

Journal or seriesEvolutionary Applications



Publication year2014


Issue number9

Pages range1107-1119


Publication countryUnited Kingdom

Publication languageEnglish


Persistent website addresshttp://onlinelibrary.wiley.com/doi/10.1111/eva.12145/pdf

Research data linkhttp://dx.doi.org/10.5061/dryad.10154

Publication open accessOpenly available

Publication channel open accessOpen Access channel

Publication is parallel published (JYX)https://jyx.jyu.fi/handle/123456789/44534


Understanding the effects of inbreeding and genetic drift within populations and hybridization between genetically differentiated populations is important for many basic and applied questions in ecology and evolutionary biology. The magnitudes and even the directions of these effects can be influenced by various factors, especially by the current and historical population size (i.e. inbreeding rate). Using Drosophila littoralis as a model species, we studied the effect of inbreeding rate over a range of inbreeding levels on (i) mean fitness of a population (relative to that of an outbred control population), (ii) within‐population inbreeding depression (reduction in fitness of offspring from inbred versus random mating within a population) and (iii) heterosis (increase in fitness of offspring from interpopulation versus within‐population random mating). Inbreeding rate was manipulated by using three population sizes (2, 10 and 40), and fitness was measured as offspring survival and fecundity. Fast inbreeding (smaller effective population size) resulted in greater reduction in population mean fitness than slow inbreeding, when populations were compared over similar inbreeding coefficients. Correspondingly, populations with faster inbreeding expressed more heterosis upon interpopulation hybridization. Inbreeding depression within the populations did not have a clear relationship with either the rate or the level of inbreeding.

Free keywordsgenetic distance; genetic divergence; genetic drift; interpopulation hybridization; population size

Contributing organizations

Ministry reportingYes

Reporting Year2014

JUFO rating2

Last updated on 2024-09-05 at 23:26