A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Resting Energy Expenditure, Metabolic and Sex Hormones in Two Phases of the Menstrual and Hormonal Contraceptive Cycles (2024)
Löfberg, I. E., Karppinen, J. E., Laatikainen-Raussi, V., Lehti, M., Hackney, A. C., Ihalainen, J. K., & Mikkonen, R. S. (2024). Resting Energy Expenditure, Metabolic and Sex Hormones in Two Phases of the Menstrual and Hormonal Contraceptive Cycles. Medicine and Science in Sports and Exercise, ahead of Print . https://doi.org/10.1249/mss.0000000000003518
JYU-tekijät tai -toimittajat
Julkaisun tiedot
Julkaisun kaikki tekijät tai toimittajat: Löfberg, Ida E.; Karppinen, Jari E.; Laatikainen-Raussi, Vesa; Lehti, Maarit; Hackney, Anthony C.; Ihalainen, Johanna K.; Mikkonen, Ritva S.
Lehti tai sarja: Medicine and Science in Sports and Exercise
ISSN: 0195-9131
eISSN: 1530-0315
Julkaisuvuosi: 2024
Ilmestymispäivä: 01.08.2024
Volyymi: ahead of Print
Kustantaja: Lippincott Williams & Wilkins
Julkaisumaa: Yhdysvallat (USA)
Julkaisun kieli: englanti
DOI: https://doi.org/10.1249/mss.0000000000003518
Julkaisun avoin saatavuus: Ei avoin
Julkaisukanavan avoin saatavuus:
Julkaisu on rinnakkaistallennettu (JYX): https://jyx.jyu.fi/handle/123456789/96775
Tiivistelmä
Resting energy expenditure (REE) may fluctuate during the menstrual cycle (MC), due to the physiological effects of estradiol (E2) and progesterone (P4). This study examined changes in REE and metabolic hormones (leptin, ghrelin, thyroid hormones), and dietary intake in two hormonally distinct groups, naturally menstruating women (NoOC) and women using monophasic combined oral contraceptives (COC).
Methods
Measurements included REE by indirect calorimetry, body composition by bioimpedance, and blood samples for hormone analysis in the early follicular and mid-luteal phases of the MC in NoOC-group (n = 38) or the active and inactive phases of the COC cycle (COC, n = 19). Participants recorded their food intake for 3 days after measurements. A secondary analysis was completed for the NoOC-group without REE outliers (difference between measurements >1.5 × interquartile range, n = 4).
Results
In the NoOC-group, luteal phase REE was 40 kcal higher than follicular phase REE [95% confidence interval (CI): -2 kcal/d–82 kcal/d, d = 0.20, p = 0.061]. Leptin (d = 0.35, p < 0.001), T3 (d = 0.26, p = 0.05) and fat intake (d = 0.48, p = 0.027) were lower, and T4 (d = 0.21, p = 0.041) was higher in the luteal phase. After excluding outliers, REE was 44 kcal higher in the luteal phase than in the follicular phase (95% CI: 12 kcal/d–76 kcal/d, d = 0.22, p = 0.007). In the COC-group, the mean difference in REE was -2 kcal (95% CI-82 kcal/d–79 kcal/d) between active and inactive phases, while T3 was higher in the inactive phase (d = 0.01, p = 0.037).
Conclusions
REE increases only slightly from the follicular to the luteal phase but remains unchanged between COC phases. Increases in T3, leptin, and fat intake during the luteal phase might echo metabolic fluctuations that parallel female sex hormones during the MC.
YSO-asiasanat: naiset; fysiologia; energiansaanti; raskauden ehkäisy; hormonit; aineenvaihdunta; energiankulutus (aineenvaihdunta); kuukautiskierto
Vapaat asiasanat: female physiology; energy intake; hormonal contraception; reproductive hormones; resting metabolism
Liittyvät organisaatiot
Hankkeet, joissa julkaisu on tehty
- Naisten kuukautiskierto- ja kestävyysharjoittelututkimus
- Mikkonen, Ritva
- Opetus- ja kulttuuriministeriö
OKM-raportointi: Kyllä
VIRTA-lähetysvuosi: 2024
Alustava JUFO-taso: 3
