A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Association Between Exercise Systolic Blood Pressure and Risk of Stroke in Men With and Without Cardiovascular Disease (2024)
Jae, S. Y., Gwon, J. G., Kurl, S., Kunutsor, S. K., & Laukkanen, J. A. (2024). Association Between Exercise Systolic Blood Pressure and Risk of Stroke in Men With and Without Cardiovascular Disease. Journal of Cardiopulmonary Rehabilitation and Prevention, 44(5), 377-381. https://doi.org/10.1097/HCR.0000000000000889
JYU-tekijät tai -toimittajat
Julkaisun tiedot
Julkaisun kaikki tekijät tai toimittajat: Jae, Sae Young; Gwon, Jun Gyo; Kurl, Sudhir; Kunutsor, Setor K.; Laukkanen, Jari A.
Lehti tai sarja: Journal of Cardiopulmonary Rehabilitation and Prevention
ISSN: 1932-7501
eISSN: 1932-751X
Julkaisuvuosi: 2024
Ilmestymispäivä: 03.09.2024
Volyymi: 44
Lehden numero: 5
Artikkelin sivunumerot: 377-381
Kustantaja: Lippincott
Julkaisumaa: Yhdysvallat (USA)
Julkaisun kieli: englanti
DOI: https://doi.org/10.1097/HCR.0000000000000889
Julkaisun avoin saatavuus: Ei avoin
Julkaisukanavan avoin saatavuus:
Tiivistelmä
We tested the hypothesis that an exaggerated exercise systolic blood pressure (ESBP) would be associated with the risk of stroke in men with and without a history of cardiovascular disease (CVD).
Methods:
An ESBP was defined as a maximal systolic blood pressure (SBP) ≥ 210 mmHg during graded exercise testing on a stationary bike until volitional fatigue in 2410 men aged 42 to 61 yr at baseline.
Results:
Over a median 27-yr follow-up, 419 incident stroke events occurred. In a multivariable adjusted model, men with an ESBP had a significantly increased risk of stroke in the entire cohort (HR = 1.41: 95% CI, 1.15-1.74). This association was still significant following further adjustment for resting SBP (HR = 1.25: 95% CI, 1.01-1.56). In subgroup analysis, ESBP was modestly associated with an increased risk of stroke in men with a history of CVD (HR = 1.37: 95% CI, 0.98-1.93), with no strong evidence of an association in men without a history of CVD (HR = 1.20: 95% CI, 0.90-1.60).
Conclusions:
These findings suggest that the heightened risk of stroke related to ESBP response in a general population-based sample of men may be primarily driven by a history of CVD. The results underscore the importance of considering exercise blood pressure response when interpreting stress tests, particularly in individuals with pre-existing CVD.
YSO-asiasanat: verenpaine; kohonnut verenpaine; fyysinen rasitus; sydäninfarkti; sydän- ja verisuonitaudit; miehet; seurantatutkimus
Liittyvät organisaatiot
OKM-raportointi: Kyllä
VIRTA-lähetysvuosi: 2024
Alustava JUFO-taso: 1