A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Association Between Exercise Systolic Blood Pressure and Risk of Stroke in Men With and Without Cardiovascular Disease (2024)


Jae, S. Y., Gwon, J. G., Kurl, S., Kunutsor, S. K., & Laukkanen, J. A. (2024). Association Between Exercise Systolic Blood Pressure and Risk of Stroke in Men With and Without Cardiovascular Disease. Journal of Cardiopulmonary Rehabilitation and Prevention, 44(5), 377-381. https://doi.org/10.1097/HCR.0000000000000889


JYU-tekijät tai -toimittajat


Julkaisun tiedot

Julkaisun kaikki tekijät tai toimittajatJae, Sae Young; Gwon, Jun Gyo; Kurl, Sudhir; Kunutsor, Setor K.; Laukkanen, Jari A.

Lehti tai sarjaJournal of Cardiopulmonary Rehabilitation and Prevention

ISSN1932-7501

eISSN1932-751X

Julkaisuvuosi2024

Ilmestymispäivä03.09.2024

Volyymi44

Lehden numero5

Artikkelin sivunumerot377-381

KustantajaLippincott

JulkaisumaaYhdysvallat (USA)

Julkaisun kielienglanti

DOIhttps://doi.org/10.1097/HCR.0000000000000889

Julkaisun avoin saatavuusEi avoin

Julkaisukanavan avoin saatavuus


Tiivistelmä

Purpose:
We tested the hypothesis that an exaggerated exercise systolic blood pressure (ESBP) would be associated with the risk of stroke in men with and without a history of cardiovascular disease (CVD).

Methods:
An ESBP was defined as a maximal systolic blood pressure (SBP) ≥ 210 mmHg during graded exercise testing on a stationary bike until volitional fatigue in 2410 men aged 42 to 61 yr at baseline.

Results:
Over a median 27-yr follow-up, 419 incident stroke events occurred. In a multivariable adjusted model, men with an ESBP had a significantly increased risk of stroke in the entire cohort (HR = 1.41: 95% CI, 1.15-1.74). This association was still significant following further adjustment for resting SBP (HR = 1.25: 95% CI, 1.01-1.56). In subgroup analysis, ESBP was modestly associated with an increased risk of stroke in men with a history of CVD (HR = 1.37: 95% CI, 0.98-1.93), with no strong evidence of an association in men without a history of CVD (HR = 1.20: 95% CI, 0.90-1.60).

Conclusions:
These findings suggest that the heightened risk of stroke related to ESBP response in a general population-based sample of men may be primarily driven by a history of CVD. The results underscore the importance of considering exercise blood pressure response when interpreting stress tests, particularly in individuals with pre-existing CVD.


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Liittyvät organisaatiot


OKM-raportointiKyllä

VIRTA-lähetysvuosi2024

Alustava JUFO-taso1


Viimeisin päivitys 2024-14-10 klo 15:08