A2 Review article, Literature review, Systematic review
Why (k)not? (2025)

You, N., & Cougnon, F. B. (2025). Why (k)not?. Trends in Chemistry, 7(1), 7-10. https://doi.org/10.1016/j.trechm.2024.11.006

JYU authors or editors

You, Nadege
Cougnon, Fabien

Publication details

All authors or editors: You, Nadège; Cougnon, Fabien B.L.

Journal or series: Trends in Chemistry

ISSN: 2589-5974

eISSN: 2589-5974

Publication year: 2025

Volume: 7

Issue number: 1

Pages range: 7-10

Publisher: Elsevier

Publication country: United States

Publication language: English

DOI: https://doi.org/10.1016/j.trechm.2024.11.006

Publication open access: Openly available

Publication channel open access: Partially open access channel

Publication is parallel published (JYX): https://jyx.jyu.fi/handle/123456789/99889

Abstract

The functions of synthetic macromolecules are currently limited by our inability to control their folding beyond static secondary structures. Introducing mechanical entanglements may provide a solution to this problem by enabling the creation of new types of folded structures that can undergo complex conformational transformations in response to external stimuli.

Keywords: self-assembly (chemistry); molecules; macromolecules; nanostructures

Free keywords: molecular topology; foldamer; molecular folding; conformational control; knot; catenane; self-assembly

Fields of science: