A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Protonation of a Spherical Macrotricyclic Tetramine : Water Inclusion, Allosteric Effect, and Cooperativity (2018)

Graf, E., Harrowfield, J., Kintzinger, J.-P., Lehn, J.-M., Moigne, J. L., & Rissanen, K. (2018). Protonation of a Spherical Macrotricyclic Tetramine : Water Inclusion, Allosteric Effect, and Cooperativity. ChemPlusChem, 83(7), 605-611. https://doi.org/10.1002/cplu.201700557

JYU-tekijät tai -toimittajat

Rissanen, Kari

Julkaisun tiedot

Julkaisun kaikki tekijät tai toimittajat: Graf, Ernest; Harrowfield, Jack; Kintzinger, Jean-Pierre; Lehn, Jean-Marie; Moigne, Jacques Le; Rissanen, Kari

Lehti tai sarja: ChemPlusChem

ISSN: 2192-6506

eISSN: 2192-6506

Julkaisuvuosi: 2018

Volyymi: 83

Lehden numero: 7

Artikkelin sivunumerot: 605-611

Kustantaja: Wiley-VCH-Verlag

Julkaisumaa: Saksa

Julkaisun kieli: englanti

DOI: https://doi.org/10.1002/cplu.201700557

Julkaisun avoin saatavuus: Ei avoin

Julkaisukanavan avoin saatavuus:

Lisätietoja: This article also appears in: Professor Leone Spiccia Memorial Issue

Tiivistelmä

The spherical macrotricyclic cryptand tetramine “C24” (1) displays remarkable protonation behaviour. It undergoes protonation in four successive steps for which pKa values of 11.17±0.05, 10.28±0.04, 6.00±0.06 and 3.08±0.08 have been determined at 298 K. The unusually close values for the first two protonations provide evidence for the encapsulation of a water molecule serving as effector for the second protonation, which is consistent with earlier observations that the exchange of protons bound in the diprotonated species with solvent protons is unusually slow and that 17O NMR spectra show the presence of an oxygen centre in the same species quite distinct from that of solvent water. Encapsulation of water is also observed in the solid state in the picrate salt of the triprotonated form of 1 and has been characterised by means of X‐ray structural determination.

YSO-asiasanat: supramolekulaarinen kemia

Vapaat asiasanat: macrocycles; tetramines; protonation

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