A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Ideal cardiovascular health and risk of acute myocardial infarction among Finnish men (2019)
Isiozor, N. M., Kunutsor, S. K., Voutilainen, A., Kurl, S., Kauhanen, J., & Laukkanen, J. A. (2019). Ideal cardiovascular health and risk of acute myocardial infarction among Finnish men. Atherosclerosis, 289, 126-131. https://doi.org/10.1016/j.atherosclerosis.2019.08.024
JYU-tekijät tai -toimittajat
Julkaisun tiedot
Julkaisun kaikki tekijät tai toimittajat: Isiozor, Nzechukwu M.; Kunutsor, Setor K.; Voutilainen, Ari; Kurl, Sudhir; Kauhanen, Jussi; Laukkanen, Jari A.
Lehti tai sarja: Atherosclerosis
ISSN: 0021-9150
eISSN: 1879-1484
Julkaisuvuosi: 2019
Volyymi: 289
Artikkelin sivunumerot: 126-131
Kustantaja: Elsevier Ireland Ltd.
Julkaisumaa: Irlanti
Julkaisun kieli: englanti
DOI: https://doi.org/10.1016/j.atherosclerosis.2019.08.024
Julkaisun avoin saatavuus: Ei avoin
Julkaisukanavan avoin saatavuus:
Julkaisu on rinnakkaistallennettu (JYX): https://jyx.jyu.fi/handle/123456789/65624
Tiivistelmä
Methods: We used the ongoing population-based Kuopio Ischaemic Heart Disease cohort study comprising men aged 40 to 62 years at baseline. The CVH metrics was computed among 2584 participants at baseline with health scores ranging from 0 to 7. This was categorized into three groups of CVH metrics as poor (0-2), intermediate (3-4) and ideal (≥5). Multivariate Cox regression models were used to estimate the hazard ratios (HR) and 95% confidence intervals (CIs) of CVH metrics for AMI.
Results: During a median follow-up period of 25.2 years, 513 cases of AMI were recorded. Only one participant was able to achieve all the seven ideal health metrics. The risk of AMI decreased continuously with increasing number of CVH metrics across the range 2-7 (for non-linearity, p=0.07). Men with ideal CVH metrics had a HR (95% CI) for AMI of 0.28 (CI 0.15 – 0.55, p<0.001) compared to those with poor CVH metrics after adjustment for age, alcohol intake and socioeconomic status.The associations remained consistent following further adjustment for history of coronary heart disease and history of type 2 diabetes.
Conclusions: Ideal CVH metrics was strongly and linearly associated with reduced risk of AMI among middle-aged Finnish men.
YSO-asiasanat: sydäninfarkti; sydän- ja verisuonitaudit; fyysinen kunto; terveydentila; riskitekijät; miehet
Vapaat asiasanat: acute myocardial infarction; cardiovascular health metrics; ideal cardiovascular health; risk factor; men
Liittyvät organisaatiot
OKM-raportointi: Kyllä
Raportointivuosi: 2019
JUFO-taso: 2
