G5 Doctoral dissertation (article)
Supramolecular chemistry of anion-binding receptors based on concave macrocycles (2019)


Kiesilä, A. (2019). Supramolecular chemistry of anion-binding receptors based on concave macrocycles [Doctoral dissertation]. Jyväskylän yliopisto. JYU dissertations, 137. http://urn.fi/URN:ISBN:978-951-39-7855-6


JYU authors or editors


Publication details

All authors or editors: Kiesilä, Anniina

eISBN: 978-951-39-7855-6

Journal or series: JYU dissertations

eISSN: 2489-9003

Publication year: 2019

Number in series: 137

Number of pages in the book: 1 verkkoaineisto (68 sivua, 24 sivua useina numerointijaksoina, 27 numeroimatonta sivua)

Publisher: Jyväskylän yliopisto

Place of Publication: Jyväskylä

Publication country: Finland

Publication language: English

Persistent website address: http://urn.fi/URN:ISBN:978-951-39-7855-6

Publication open access: Openly available

Publication channel open access: Open Access channel


Abstract

This thesis describes the supramolecular chemistry of different anion-binding host molecules with a special focus on pyridine[4]arenes. The first part of the thesis gives a brief introduction to supramolecular chemistry and its special features, host-guest chemistry and self-assembly. Later on, a short review of different hosts is presented, especially focusing on those utilized in the experimental part of the thesis. In the second part of the thesis an introduction is presented to the structural analyzation techniques utilized in the experimental part. A special focus is set on ion mobility mass spectrometry, a relatively new technique for structural characterization of supramolecular complexes. The third part presents the summary of experimental work. The binding properties of pyridinearene turned out to completely differ from previous reports in the literature. New binding features of pyridinearene were discovered, such as simultaneous endo- and exo-complex formation with neutral and anionic guests. The formation of the hexameric assembly of pyridinearene was also observed for the first time in gas phase and in solid state. In solution, the thermodynamic balance in self-assembly was revealed. Different analyzation techniques have been utilized in the structural characterisation of pyridinearenes. Ion mobility mass spectrometry proved to be spectacular for structural characterization of the gas phase assemblies. As a new technique, its utilization for structural chemistry is demonstrated in the experimental part with several examples. In this thesis, also the binding properties of cyclohexylhemicucurbit[8]uril and crown ether urea receptors were revealed and thoroughly studied in gas phase, solution and in solid state.


Keywords: supramolecular chemistry; chemical bonds; mass spectrometry; x-ray crystallography

Free keywords: pyridine[4]arene; ion mobility mass spectrometry; self-assembly; anion binding


Contributing organizations


Ministry reporting: Yes

Reporting Year: 2019


Last updated on 2021-10-06 at 14:15