A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Brain and behavioral alterations in subjects with social anxiety dominated by empathic embarrassment (2020)

Tei, S., Kauppi, J.-P., Jankowski, K. F., Fujino, J., Monti, R. P., Tohka, J., Abe, N., Murai, T., Takahashi, H., & Hari, R. (2020). Brain and behavioral alterations in subjects with social anxiety dominated by empathic embarrassment. Proceedings of the National Academy of Sciences of the United States of America, 117(8), 4385-4391. https://doi.org/10.1073/pnas.1918081117

JYU-tekijät tai -toimittajat

Julkaisun tiedot

Julkaisun kaikki tekijät tai toimittajat: Tei, Shisei; Kauppi, Jukka-Pekka; Jankowski, Kathryn F.; Fujino, Junya; Monti, Ricardo P.; Tohka, Jussi; Abe, Nobuhito; Murai, Toshiya; Takahashi, Hidehiko; Hari, Riitta

Lehti tai sarja: Proceedings of the National Academy of Sciences of the United States of America

ISSN: 0027-8424

eISSN: 1091-6490

Julkaisuvuosi: 2020

Volyymi: 117

Lehden numero: 8

Artikkelin sivunumerot: 4385-4391

Kustantaja: National Academy of Sciences

Julkaisumaa: Yhdysvallat (USA)

Julkaisun kieli: englanti

DOI: https://doi.org/10.1073/pnas.1918081117

Julkaisun avoin saatavuus: Avoimesti saatavilla

Julkaisukanavan avoin saatavuus: Osittain avoin julkaisukanava

Julkaisu on rinnakkaistallennettu (JYX): https://jyx.jyu.fi/handle/123456789/67916

Tiivistelmä

Social-anxiety disorder involves a fear of embarrassing oneself in the presence of others. Taijin-kyofusho (TKS), a subtype common in East Asia, additionally includes a fear of embarrassing others. TKS individuals are hypersensitive to others' feelings and worry that their physical or behavioral defects humiliate others. To explore the underlying neurocognitive mechanisms, we compared TKS ratings with questionnaire-based empathic disposition, cognitive flexibility (set-shifting), and empathy-associated brain activity in 23 Japanese adults. During 3-tesla functional MRI, subjects watched video clips of badly singing people who expressed either authentic embarrassment (EMBAR) or hubristic pride (PRIDE). We expected the EMBAR singers to embarrass the viewers via emotion-sharing involving affective empathy (affEMP), and the PRIDE singers to embarrass via perspective-taking involving cognitive empathy (cogEMP). During affEMP (EMBAR > PRIDE), TKS scores correlated positively with dispositional affEMP (personal-distress dimension) and with amygdala activity. During cogEMP (EMBAR < PRIDE), TKS scores correlated negatively with cognitive flexibility and with activity of the posterior superior temporal sulcus/temporoparietal junction (pSTS/TPJ). Intersubject correlation analysis implied stronger involvement of the anterior insula, inferior frontal gyrus, and premotor cortex during affEMP than cogEMP and stronger involvement of the medial prefrontal cortex, posterior cingulate cortex, and pSTS/TPJ during cogEMP than affEMP. During cogEMP, the whole-brain functional connectivity was weaker the higher the TKS scores. The observed imbalance between affEMP and cogEMP, and the disruption of functional brain connectivity, likely deteriorate cognitive processing during embarrassing situations in persons who suffer from other-oriented social anxiety dominated by empathic embarrassment.

YSO-asiasanat: sosiaalisten tilanteiden pelko; empatia; toiminnallinen magneettikuvaus

Vapaat asiasanat: embarrassment; empathy; functional magnetic resonance imaging; intersubject correlation; social anxiety

Liittyvät organisaatiot

OKM-raportointi: Kyllä

Raportointivuosi: 2020

JUFO-taso: 3