A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Exercise cardiac power and the risk of heart failure in men : A population-based follow-up study (2020)


Kurl, Sudhir; Jae, Sae Young; Mäkikallio, Timo H.; Voutilainen, Ari; Hagnäs, Magnus J.; Kauhanen, Jussi; Laukkanen, Jari A. (2020). Exercise cardiac power and the risk of heart failure in men : A population-based follow-up study. Journal of Sport and Health Science, Early online. DOI: 10.1016/j.jshs.2020.02.008


JYU-tekijät tai -toimittajat


Julkaisun tiedot

Julkaisun kaikki tekijät tai toimittajat: Kurl, Sudhir; Jae, Sae Young; Mäkikallio, Timo H.; Voutilainen, Ari; Hagnäs, Magnus J.; Kauhanen, Jussi; Laukkanen, Jari A.

Lehti tai sarja: Journal of Sport and Health Science

ISSN: 2095-2546

eISSN: 2213-2961

Julkaisuvuosi: 2020

Volyymi: Early online

Kustantaja: Elsevier

Julkaisumaa: Alankomaat

Julkaisun kieli: englanti

DOI: http://doi.org/10.1016/j.jshs.2020.02.008

Avoin saatavuus: Open access -julkaisukanavassa ilmestynyt julkaisu

Julkaisu on rinnakkaistallennettu (JYX): https://jyx.jyu.fi/handle/123456789/67979


Tiivistelmä

Background
Little is known about exercise cardiac power (ECP), defined as the ratio of directly measured maximal oxygen uptake with peak systolic blood pressure during exercise on heart failure (HF) risk. We examined the association of ECP and the risk of HF.

Methods
This was a population-based cohort study of 2351 men from eastern Finland. The average time to follow-up was 25 years. Participants participated at baseline in an exercise stress test. A total of 313 cases of HF occurred.

Results
Men with low ECP (<9.84 mL/mmHg, lowest quartile) had a 2.37-fold (95% confidence interval (CI): 1.68 − 3.35, p < 0.0001) hazards ratio of HF as compared with men with high ECP (>13.92 mL/mmHg, highest quartile), after adjusting for age. Low ECP was associated with a 1.96-fold risk (95%CI: 1.38 − 2.78, p < 0.001) of HF after additional adjustment for conventional risk factors. After further adjustment for left ventricular hypertrophy, the results hardly changed (hazards ratio = 1.87, 95%CI: 1.31 − 2.66, p < 0.001). One SD increase in ECP (3.16 mL/mmHg) was associated with a decreased risk of HF by 28% (95%CI: 17% − 37%).

Conclusion
ECP provides a non-invasive and easily available measure from cardiopulmonary exercise test in predicting HF. However, ECP did not provide additional value over maximal oxygen uptake.


YSO-asiasanat: sydän; liikunta; fyysinen aktiivisuus; maksimaalinen hapenotto; sydämen vajaatoiminta; sydän- ja verisuonitaudit; miehet

Vapaat asiasanat: exercise cardiac power; heart failure; men


Liittyvät organisaatiot


OKM-raportointi: Ei, julkaisuprosessissa

Alustava JUFO-taso: 1


Viimeisin päivitys 2020-18-08 klo 13:42