A1 Journal article (refereed)
Asymmetric hydrogenation of an α-unsaturated carboxylic acid catalyzed by intact chiral transition metal carbonyl cluster : diastereomeric control of enantioselectivity (2020)

Abdel-Magied, A. F., Theibich, Y., Singh, A. K., Rahaman, A., Doverbratt, I., Raha, A. K., Haukka, M., Richmond, M. G., & Nordlander, E. (2020). Asymmetric hydrogenation of an α-unsaturated carboxylic acid catalyzed by intact chiral transition metal carbonyl cluster : diastereomeric control of enantioselectivity. Dalton Transactions, 49(14), 4244-4256. https://doi.org/10.1039/C9DT04799A

JYU authors or editors

Haukka, Matti

Publication details

All authors or editors: Abdel-Magied, Ahmed F.; Theibich, Yusuf; Singh, Amrendra K.; Rahaman, Ahibur; Doverbratt, Isa; Raha, Arun K.; Haukka, Matti; Richmond, Michael G.; Nordlander, Ebbe

Journal or series: Dalton Transactions

ISSN: 1477-9226

eISSN: 1477-9234

Publication year: 2020

Volume: 49

Issue number: 14

Pages range: 4244-4256

Publisher: Royal Society of Chemistry

Publication country: United Kingdom

Publication language: English

DOI: https://doi.org/10.1039/C9DT04799A

Publication open access: Openly available

Publication channel open access: Partially open access channel

Publication is parallel published (JYX): https://jyx.jyu.fi/handle/123456789/72990

Abstract

Twenty clusters of the general formula [(μ-H)2Ru3(μ3-S)(CO)7(μ-P–P*)] (P–P* = chiral diphosphine of the ferrocene-based Walphos or Josiphos families) have been synthesised and characterised. The clusters have been tested as catalysts for asymmetric hydrogenation of tiglic acid [trans-2-methyl-2-butenoic acid]. The observed enantioselectivities and conversion rates strongly support catalysis by intact Ru3 clusters. A catalytic mechanism involving an active Ru3 catalyst generated by CO loss from [(μ-H)2Ru3(μ3-S)(CO)7(μ-P–P*)] has been investigated by DFT calculations.

Keywords: catalysis; carboxylic acids

Free keywords: asymmetric hydrogenation; carboxylic acid

Fields of science:

116 Chemical sciences (Natural sciences)

Contributing organizations

JYU units:

Department of Chemistry

Ministry reporting: Yes

VIRTA submission year: 2020

JUFO rating: 1

A1 Journal article (refereed)Asymmetric hydrogenation of an α-unsaturated carboxylic acid catalyzed by intact chiral transition metal carbonyl cluster : diastereomeric control of enantioselectivity (2020)

JYU authors or editors

Publication details

Abstract

Contributing organizations

A1 Journal article (refereed)
Asymmetric hydrogenation of an α-unsaturated carboxylic acid catalyzed by intact chiral transition metal carbonyl cluster : diastereomeric control of enantioselectivity (2020)