A1 Journal article (refereed)
A Novel Halogen Bond Acceptor : 1-(4-Pyridyl)-4-Thiopyridine (PTP) Zwitterion (2020)

Ding, X., Tuikka, M., & Haukka, M. (2020). A Novel Halogen Bond Acceptor : 1-(4-Pyridyl)-4-Thiopyridine (PTP) Zwitterion. Crystals, 10(3), Article 165. https://doi.org/10.3390/cryst10030165

JYU authors or editors

Publication details

All authors or editors: Ding, Xin; Tuikka, Matti; Haukka, Matti

Journal or series: Crystals

eISSN: 2073-4352

Publication year: 2020

Volume: 10

Issue number: 3

Article number: 165

Publisher: MDPI

Publication country: Switzerland

Publication language: English

DOI: https://doi.org/10.3390/cryst10030165

Publication open access: Openly available

Publication channel open access: Open Access channel

Publication is parallel published (JYX): https://jyx.jyu.fi/handle/123456789/68092

Abstract

Sulfur is a widely used halogen bond (XB) acceptor, but only a limited number of neutral XB acceptors with bifurcated sp3-S sites have been reported. In this work a new bidentate XB acceptor, 1-(4-pyridyl)-4-thiopyridine (PTP), which combines sp3-S and sp2-N acceptor sites, is introduced. Three halogen bonded cocrystals were obtained by using 1,4-diiodobenzene (DIB), 1,4-diiodotetrafluorobenzene (DIFB), and iodopentafluorobenzene (IPFB) as XB donors and PTP as acceptor. The structures of the cocrystals showed some XB selectivity between the S and N donors in PTP. However, the limited contribution of XB to the overall molecular packing in these three cocrystals and the results from DSC measurements clearly point out the synergetic influence and interplay of all noncovalent interactions in crystal packing of these compounds.

Keywords: sulphur compounds; organic compounds; chemical bonds; crystals

Free keywords: Halogen bonds (XB); acceptor; cocrystals; selectivity

Contributing organizations

Ministry reporting: Yes

Reporting Year: 2020

JUFO rating: 1