A1 Journal article (refereed)
Health-related Quality of Life of Breast Cancer Survivors Attending an Exercise Intervention Study : A Five-year Follow-up (2020)
Roine, E., Sintonen, H., Kellokumpu-Lehtinen, P.-L., Penttinen, H., Utriainen, M., Vehmanen, L., Huovinen, R., Kautiainen, H., Nikander, R., Blomqvist, C., & Saarto, T. (2020). Health-related Quality of Life of Breast Cancer Survivors Attending an Exercise Intervention Study : A Five-year Follow-up. In Vivo, 34(2), 667-674. https://doi.org/10.21873/invivo.11821
JYU authors or editors
Publication details
All authors or editors: Roine, Eija; Sintonen, Harri; Kellokumpu-Lehtinen, Pirkko-Liisa; Penttinen, Heidi; Utriainen, Meri; Vehmanen, Leena; Huovinen, Riika; Kautiainen, Hannu; Nikander, Riku; Blomqvist, Carl; et al.
Journal or series: In Vivo
ISSN: 0258-851X
eISSN: 1791-7549
Publication year: 2020
Volume: 34
Issue number: 2
Pages range: 667-674
Publisher: International Institute of Anticancer Research
Publication country: Greece
Publication language: English
DOI: https://doi.org/10.21873/invivo.11821
Publication open access: Openly available
Publication channel open access: Open Access channel
Publication is parallel published (JYX): https://jyx.jyu.fi/handle/123456789/68104
Abstract
Background/Aim: As the number of breast cancer survivors is increasing, their long-term health-related quality of life (HRQoL)has become an important issue. The aim of the study is to follow up the HRQoL of breast cancer survivors (BCS) in a prospectiverandomized exercise intervention study and to compare HRQoL to that of the age-matched general female population. Patients and Methods: Following adjuvant treatment, 537 patients aged 35-68 and capable of exercise training were randomized to a 12-monthexercise trial. In 182 of those patients, HRQoL was measured by the generic 15D at baseline and followed up for five years.Furthermore, the HRQoL of all BCS answering the 15D at five-year follow-up (n=390) was compared to that of a representativesample of the general population. Results: After five years, the BCS' mean HRQoL demonstrated a statistically and clinicallysignificant impairment compared to that of the general population (difference −0.023, p<0.001). The mean HRQoL of BCS followedup from baseline until five years did not improve significantly (change=0.007, p=0.27), whereas the dimensions of usual activities(0.043, p=0.004), depression (0.038, p=0.007), distress (0.030, p=0.036), and sexual activity (0.057, p=0.009) did. Conclusion:The HRQoL of BCS was still impaired five years following treatment.
Keywords: breast cancer; cancer treatments; rehabilitation; rehabilitation patients; exercise therapy; well-being; quality of life; follow-up study
Free keywords: breast cancer; cancer; exercise; general population; health-related quality of life; physical activity; quality of life; rehabilitation; utility
Contributing organizations
Ministry reporting: Yes
Reporting Year: 2020
JUFO rating: 1
