A1 Journal article (refereed)
1,2,6-Thiadiazine 1-Oxides : Unsaturated Three-Dimensional S,N-Heterocycles from Sulfonimidamides (2020)


Schöbel, J.-H., Passia, M. T., Wolter, N. A., Puttreddy, R., Rissanen, K., & Bolm, C. (2020). 1,2,6-Thiadiazine 1-Oxides : Unsaturated Three-Dimensional S,N-Heterocycles from Sulfonimidamides. Organic Letters, 12(7), 2702-2706. https://doi.org/10.1021/acs.orglett.0c00666


JYU authors or editors


Publication details

All authors or editorsSchöbel, Jan-Hendrik; Passia, Marco Thomas; Wolter, Nadja Anna; Puttreddy, Rakesh; Rissanen, Kari; Bolm, Carsten

Journal or seriesOrganic Letters

ISSN1523-7060

eISSN1523-7052

Publication year2020

Volume12

Issue number7

Pages range2702-2706

PublisherAmerican Chemical Society

Publication countryUnited States

Publication languageEnglish

DOIhttps://doi.org/10.1021/acs.orglett.0c00666

Publication open accessNot open

Publication channel open access

Publication is parallel published (JYX)https://jyx.jyu.fi/handle/123456789/68819


Abstract

Unprecedented three-dimensional 1,2,6-thiadiazine 1-oxides have been prepared by an aza-Michael-addition/cyclization/condensation reaction sequence starting from sulfonimidamides and propargyl ketones. The products have been further functionalized by standard cross-coupling reactions, selective bromination of the heterocyclic ring, and conversion into a β-hydroxy substituted derivative. A representative product was characterized by single-crystal X-ray structure analysis.


Keywordsbioactive compounds

Free keywordssulfonimidamides; single-crystal X-ray;


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Ministry reportingYes

Reporting Year2020

JUFO rating2


Last updated on 2024-03-04 at 21:26