A1 Journal article (refereed)
The Effects of Acceptance and Commitment Therapy (ACT) Intervention on Inflammation and Stress Biomarkers : a Randomized Controlled Trial (2020)


Järvelä-Reijonen, Elina; Puttonen, Sampsa; Karhunen, Leila; Sairanen, Essi; Laitinen, Jaana; Kolehmainen, Mikko; Pihlajamäki, Jussi; Kujala, Urho M.; Korpela, Riitta; Ermes, Miikka et al. (2020). The Effects of Acceptance and Commitment Therapy (ACT) Intervention on Inflammation and Stress Biomarkers : a Randomized Controlled Trial. International Journal of Behavioral Medicine, 25 (7), 539-555. DOI: 10.1007/s12529-020-09891-8


JYU authors or editors


Publication details

All authors or editors: Järvelä-Reijonen, Elina; Puttonen, Sampsa; Karhunen, Leila; Sairanen, Essi; Laitinen, Jaana; Kolehmainen, Mikko; Pihlajamäki, Jussi; Kujala, Urho M.; Korpela, Riitta; Ermes, Miikka; et al.

Journal or series: International Journal of Behavioral Medicine

ISSN: 1070-5503

eISSN: 1532-7558

Publication year: 2020

Volume: 25

Issue number: 7

Pages range: 539-555

Publisher: Springer

Publication country: United States

Publication language: English

DOI: http://doi.org/10.1007/s12529-020-09891-8

Open Access: Open access publication published in a hybrid channel

Publication is parallel published (JYX): https://jyx.jyu.fi/handle/123456789/69063


Abstract

Background
Psychological processes can be manifested in physiological health. We investigated whether acceptance and commitment therapy (ACT), targeted on psychological flexibility (PF), influences inflammation and stress biomarkers among working-age adults with psychological distress and overweight/obesity.

Method
Participants were randomized into three parallel groups: (1) ACT-based face-to-face (n = 65; six group sessions led by a psychologist), (2) ACT-based mobile (n = 73; one group session and mobile app), and (3) control (n = 66; only the measurements). Systemic inflammation and stress markers were analyzed at baseline, at 10 weeks after the baseline (post-intervention), and at 36 weeks after the baseline (follow-up). General PF and weight-related PF were measured with questionnaires (Acceptance and Action Questionnaire, Acceptance and Action Questionnaire for Weight-Related Difficulties).

Results
A group × time interaction (p = .012) was detected in the high-sensitivity C-reactive protein (hsCRP) level but not in other inflammation and stress biomarkers. hsCRP decreased significantly in the face-to-face group from week 0 to week 36, and at week 36, hsCRP was lower among the participants in the face-to-face group than in the mobile group (p = .035, post hoc test). Age and sex were stronger predictors of biomarker levels at follow-up than the post-intervention PF.

Conclusion
The results suggest that ACT delivered in group sessions may exert beneficial effects on low-grade systemic inflammation. More research is needed on how to best apply psychological interventions for the health of both mind and body among people with overweight/obesity and psychological distress.


Keywords: acceptance and commitment therapy; mindfulness; resiliency (flexibility); psychophysiology; physiological effects; overweight; stress (biological phenomena); inflammation; markers

Free keywords: psychological flexibility; ACT; mindfulness; obesity; low-grade inflammation; stress


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Ministry reporting: Yes

Preliminary JUFO rating: 1


Last updated on 2020-16-09 at 08:07