A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Discovering dynamic task-modulated functional networks with specific spectral modes using MEG (2020)

Zhu, Y., Liu, J., Ye, C., Mathiak, K., Astikainen, P., Ristaniemi, T., & Cong, F. (2020). Discovering dynamic task-modulated functional networks with specific spectral modes using MEG. NeuroImage, 218, Article 116924. https://doi.org/10.1016/j.neuroimage.2020.116924

JYU-tekijät tai -toimittajat

Julkaisun tiedot

Julkaisun kaikki tekijät tai toimittajat: Zhu, Yongjie; Liu, Jia; Ye, Chaoxiong; Mathiak, Klaus; Astikainen, Piia; Ristaniemi, Tapani; Cong, Fengyu

Lehti tai sarja: NeuroImage

ISSN: 1053-8119

eISSN: 1095-9572

Julkaisuvuosi: 2020

Volyymi: 218

Artikkelinumero: 116924

Kustantaja: Elsevier

Julkaisumaa: Alankomaat

Julkaisun kieli: englanti

DOI: https://doi.org/10.1016/j.neuroimage.2020.116924

Julkaisun avoin saatavuus: Avoimesti saatavilla

Julkaisukanavan avoin saatavuus: Osittain avoin julkaisukanava

Julkaisu on rinnakkaistallennettu (JYX): https://jyx.jyu.fi/handle/123456789/69643


Efficient neuronal communication between brain regions through oscillatory synchronization at certain frequencies is necessary for cognition. Such synchronized networks are transient and dynamic, established on the timescale of milliseconds in order to support ongoing cognitive operations. However, few studies characterizing dynamic electrophysiological brain networks have simultaneously accounted for temporal non-stationarity, spectral structure, and spatial properties. Here, we propose an analysis framework for characterizing the large-scale phase-coupling network dynamics during task performance using magnetoencephalography (MEG). We exploit the high spatiotemporal resolution of MEG to measure time-frequency dynamics of connectivity between parcellated brain regions, yielding data in tensor format. We then use a tensor component analysis (TCA)-based procedure to identify the spatio-temporal-spectral modes of covariation among separate regions in the human brain. We validate our pipeline using MEG data recorded during a hand movement task, extracting a transient motor network with beta-dominant spectral mode, which is significantly modulated by the movement task. Next, we apply the proposed pipeline to explore brain networks that support cognitive operations during a working memory task. The derived results demonstrate the temporal formation and dissolution of multiple phase-coupled networks with specific spectral modes, which are associated with face recognition, vision, and movement. The proposed pipeline can characterize the spectro-temporal dynamics of functional connectivity in the brain on the subsecond timescale, commensurate with that of cognitive performance.

YSO-asiasanat: aivotutkimus; hermoverkot (biologia); MEG; signaalinkäsittely

Vapaat asiasanat: tensor decomposition; MEG; functional connectivity; frequency-specific oscillations; dynamic brain networks; canonical polyadic decomposition

Liittyvät organisaatiot

OKM-raportointi: Kyllä

Raportointivuosi: 2020

JUFO-taso: 2

Viimeisin päivitys 2021-07-07 klo 21:33