A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Older Age Increases the Amplitude of Muscle Stretch-Induced Cortical Beta-Band Suppression But Does not Affect Rebound Strength (2020)

Walker, S., Monto, S., Piirainen, J. M., Avela, J., Tarkka, I. M., Parviainen, T. M., & Piitulainen, H. (2020). Older Age Increases the Amplitude of Muscle Stretch-Induced Cortical Beta-Band Suppression But Does not Affect Rebound Strength. Frontiers in Aging Neuroscience, 12, Article 117. https://doi.org/10.3389/fnagi.2020.00117

JYU-tekijät tai -toimittajat

Walker, Simon
Monto, Simo
Piirainen, Jarmo
Avela, Janne
Tarkka, Ina
Parviainen, Tiina
Piitulainen, Harri

Julkaisun tiedot

Julkaisun kaikki tekijät tai toimittajat: Walker, Simon; Monto, Simo; Piirainen, Jarmo M.; Avela, Janne; Tarkka, Ina M.; Parviainen, Tiina M.; Piitulainen, Harri

Lehti tai sarja: Frontiers in Aging Neuroscience

ISSN: 1663-4365

eISSN: 1663-4365

Julkaisuvuosi: 2020

Volyymi: 12

Artikkelinumero: 117

Kustantaja: Frontiers Media

Julkaisumaa: Sveitsi

Julkaisun kieli: englanti

DOI: https://doi.org/10.3389/fnagi.2020.00117

Julkaisun avoin saatavuus: Avoimesti saatavilla

Julkaisukanavan avoin saatavuus: Kokonaan avoin julkaisukanava

Julkaisu on rinnakkaistallennettu (JYX): https://jyx.jyu.fi/handle/123456789/70038

Lisätietoja: The datasets generated for this study are available on request to the corresponding author.

Tiivistelmä

Healthy aging is associated with deterioration of the sensorimotor system, which impairs balance and somatosensation. However, the exact age-related changes in the cortical processing of sensorimotor integration are unclear. This study investigated primary sensorimotor cortex (SM1) oscillations in the 15–30 Hz beta band at rest and following (involuntary) rapid stretches to the triceps surae muscles (i.e., proprioceptive stimulation) of young and older adults. A custom-built, magnetoencephalography (MEG)-compatible device was used to deliver rapid (190°·s⁻¹) ankle rotations as subjects sat passively in a magnetically-shielded room while MEG recorded their cortical signals. Eleven young (age 25 ± 3 years) and 12 older (age 70 ± 3 years) adults matched for physical activity level demonstrated clear 15–30 Hz beta band suppression and rebound in response to the stretches. A sub-sample (10 young and nine older) were tested for dynamic balance control on a sliding platform. Older adults had greater cortical beta power pre-stretch (e.g., right leg: 4.0 ± 1.6 fT vs. 5.6 ± 1.7 fT, P = 0.044) and, subsequently, greater normalized movement-related cortical beta suppression post-proprioceptive stimulation (e.g., right leg: −5.8 ± 1.3 vs. −7.6 ± 1.7, P = 0.01) than young adults. Furthermore, poorer balance was associated with stronger cortical beta suppression following proprioceptive stimulation (r = −0.478, P = 0.038, n = 19). These results provide further support that cortical processing of proprioception is hindered in older adults, potentially (adversely) influencing sensorimotor integration. This was demonstrated by the impairment of prompt motor action control, i.e., regaining perturbed balance. Finally, SM1 cortex beta suppression to a proprioceptive stimulus seems to indicate poorer sensorimotor functioning in older adults.

YSO-asiasanat: ikääntyminen; motoriikka; liikeaisti; lihasvoima; MEG

Vapaat asiasanat: event-related desynchronization (ERD); sensorimotor; lower limbs; proprioception; somatosensory processing; MEG

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