A1 Journal article (refereed)
C,N-chelated diaminocarbene platinum(II) complexes derived from 3,4-diaryl-1H-pyrrol-2,5-diimines and cis-dichlorobis(isonitrile)platinum(II): Synthesis, cytotoxicity, and catalytic activity in hydrosilylation reactions (2020)


Afanasenko, Anastasiia M.; Chulkova, Tatiana G.; Boyarskaya, Irina A.; Islamova, Regina M.; Legin, Anton A.; Keppler, Bernhard K.; Selivanov, Stanislav I.; Vereshchagin, Anatoly N. et al. (2020). C,N-chelated diaminocarbene platinum(II) complexes derived from 3,4-diaryl-1H-pyrrol-2,5-diimines and cis-dichlorobis(isonitrile)platinum(II): Synthesis, cytotoxicity, and catalytic activity in hydrosilylation reactions. Journal of Organometallic Chemistry, 923, 121435. DOI: 10.1016/j.jorganchem.2020.121435


JYU authors or editors


Publication details

All authors or editors: Afanasenko, Anastasiia M.; Chulkova, Tatiana G.; Boyarskaya, Irina A.; Islamova, Regina M.; Legin, Anton A.; Keppler, Bernhard K.; Selivanov, Stanislav I.; Vereshchagin, Anatoly N.; Elinson, Michail N.; Haukka, Matti

Journal or series: Journal of Organometallic Chemistry

ISSN: 0022-328X

eISSN: 1872-8561

Publication year: 2020

Volume: 923

Article number: 121435

Publisher: Elsevier BV

Publication country: Netherlands

Publication language: English

DOI: https://doi.org/10.1016/j.jorganchem.2020.121435

Open Access: Publication channel is not openly available

Publication is parallel published (JYX): https://jyx.jyu.fi/handle/123456789/71314


Abstract

The reaction of 3,4-diaryl-1H-pyrrol-2,5-diimines with cis-dichlorobis(isonitrile)platinum(II) affords the C,N-chelated diaminocarbene platinum(II) complexes, which have been fully characterized including molecular spectroscopy, single crystal X-ray diffraction and DFT calculations. The obtained platinum(II) complexes are effective catalysts for the hydrosilylation of alkynes and alkenes. Thus, the reaction of phenylacetylene with triethoxysilane leads to the formation of α- and β-(E)-vinylsilanes, generating TON's in the range of 103 to 104 and TOF's in the range of 102 to 103 h−1. Also, the cross-linked silicones, possessing the luminescence properties, were obtained by the hydrosilylation reaction of vinyl- and hydride-containing polysiloxanes. Additionally, the efficiency of diaminocarbene platinum(II) complexes against CH1/PA-1, SW480, and A549 cancer cell lines has been demonstrated by in vitro cytotoxicity studies.


Free keywords: anti-cancer activity; catalysis; diaminocarbene platinum(II) complexes; hydrosilylation; luminescence


Contributing organizations


Ministry reporting: Yes


Last updated on 2020-03-08 at 10:42