A1 Journal article (refereed)
Iron(III) chloride as mild catalyst for the dearomatizing cyclization of N-acylindoles (2020)

Zhang, J., Li, J., Ward, J. S., Truong, K.-N., Rissanen, K., & Albrecht, M. (2020). Iron(III) chloride as mild catalyst for the dearomatizing cyclization of N-acylindoles. Journal of Organic Chemistry, 85(19), 12160-12174. https://doi.org/10.1021/acs.joc.0c01373

JYU authors or editors

Publication details

All authors or editorsZhang, Jingyu; Li, Jing; Ward, Jas S; Truong, Khai-Nghi; Rissanen, Kari; Albrecht, Markus

Journal or seriesJournal of Organic Chemistry



Publication year2020

Publication date28/08/2020


Issue number19

Pages range12160-12174

PublisherAmerican Chemical Society (ACS)

Publication countryUnited States

Publication languageEnglish


Publication open accessNot open

Publication channel open access

Publication is parallel published (JYX)https://jyx.jyu.fi/handle/123456789/71659


A catalytic approach for the preparation of indolines by dearomatizing cyclization is presented. FeCl3 acts as a catalyst to afford tetracyclic 5a,6-dihydro-12H-indolo[2,1-b][1,3]benzoxazin-12-ones in good yields. The cyclization also proceeds with tosylamides forming C-N bonds in 53 % yield.

Keywordscatalysiscatalystsorganic chemistrychemical compounds

Free keywordsindoliini

Contributing organizations

Ministry reportingYes

Reporting Year2020

JUFO rating2

Last updated on 2024-03-04 at 21:06