A1 Journal article (refereed)
Tips and turns of bacteriophytochrome photoactivation (2020)

Takala, H., Edlund, P., Ihalainen, J. A., & Westenhoff, S. (2020). Tips and turns of bacteriophytochrome photoactivation. Photochemical and Photobiological Sciences, 19(11), 1488-1510. https://doi.org/10.1039/D0PP00117A

JYU authors or editors

Publication details

All authors or editors: Takala, Heikki; Edlund, Petra; Ihalainen, Janne A.; Westenhoff, Sebastian

Journal or series: Photochemical and Photobiological Sciences

ISSN: 1474-905X

eISSN: 1474-9092

Publication year: 2020

Volume: 19

Issue number: 11

Pages range: 1488-1510

Publisher: Royal Society of Chemistry (RSC)

Publication country: United Kingdom

Publication language: English

DOI: https://doi.org/10.1039/D0PP00117A

Publication open access: Openly available

Publication channel open access: Partially open access channel

Publication is parallel published (JYX): https://jyx.jyu.fi/handle/123456789/72404


Phytochromes are ubiquitous photosensor proteins, which control the growth, reproduction and movement in plants, fungi and bacteria. Phytochromes switch between two photophysical states depending on the light conditions. In analogy to molecular machines, light absorption induces a series of structural changes that are transduced from the bilin chromophore, through the protein, and to the output domains. Recent progress towards understanding this structural mechanism of signal transduction has been manifold. We describe this progress with a focus on bacteriophytochromes. We describe the mechanism along three structural tiers, which are the chromophore-binding pocket, the photosensory module, and the output domains. We discuss possible interconnections between the tiers and conclude by presenting future directions and open questions. We hope that this review may serve as a compendium to guide future structural and spectroscopic studies designed to understand structural signaling in phytochromes.

Keywords: photochemistry; photobiology; proteins; bacteria

Free keywords: bacteriophytochrome photoactivation

Contributing organizations

Ministry reporting: Yes

Reporting Year: 2020

JUFO rating: 1

Last updated on 2022-20-09 at 14:59