A1 Journal article (refereed)
Tips and turns of bacteriophytochrome photoactivation (2020)
Takala, H., Edlund, P., Ihalainen, J. A., & Westenhoff, S. (2020). Tips and turns of bacteriophytochrome photoactivation. Photochemical and Photobiological Sciences, 19(11), 1488-1510. https://doi.org/10.1039/D0PP00117A
JYU authors or editors
Publication details
All authors or editors: Takala, Heikki; Edlund, Petra; Ihalainen, Janne A.; Westenhoff, Sebastian
Journal or series: Photochemical and Photobiological Sciences
ISSN: 1474-905X
eISSN: 1474-9092
Publication year: 2020
Volume: 19
Issue number: 11
Pages range: 1488-1510
Publisher: Royal Society of Chemistry (RSC)
Publication country: United Kingdom
Publication language: English
DOI: https://doi.org/10.1039/D0PP00117A
Publication open access: Openly available
Publication channel open access: Partially open access channel
Publication is parallel published (JYX): https://jyx.jyu.fi/handle/123456789/72404
Abstract
Phytochromes are ubiquitous photosensor proteins, which control the growth, reproduction and movement in plants, fungi and bacteria. Phytochromes switch between two photophysical states depending on the light conditions. In analogy to molecular machines, light absorption induces a series of structural changes that are transduced from the bilin chromophore, through the protein, and to the output domains. Recent progress towards understanding this structural mechanism of signal transduction has been manifold. We describe this progress with a focus on bacteriophytochromes. We describe the mechanism along three structural tiers, which are the chromophore-binding pocket, the photosensory module, and the output domains. We discuss possible interconnections between the tiers and conclude by presenting future directions and open questions. We hope that this review may serve as a compendium to guide future structural and spectroscopic studies designed to understand structural signaling in phytochromes.
Keywords: photochemistry; photobiology; proteins; bacteria
Free keywords: bacteriophytochrome photoactivation
Contributing organizations
Ministry reporting: Yes
VIRTA submission year: 2020
JUFO rating: 1
