A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Gating Patterns to Proprioceptive Stimulation in Various Cortical Areas : An MEG Study in Children and Adults using Spatial ICA (2021)

Vallinoja, J., Jaatela, J., Nurmi, T., & Piitulainen, H. (2021). Gating Patterns to Proprioceptive Stimulation in Various Cortical Areas : An MEG Study in Children and Adults using Spatial ICA. Cerebral Cortex, 31(3), 1523-1537. https://doi.org/10.1093/cercor/bhaa306

JYU-tekijät tai -toimittajat

Julkaisun tiedot

Julkaisun kaikki tekijät tai toimittajat: Vallinoja, Jaakko; Jaatela, Julia; Nurmi, Timo; Piitulainen, Harri

Lehti tai sarja: Cerebral Cortex

ISSN: 1047-3211

eISSN: 1460-2199

Julkaisuvuosi: 2021

Volyymi: 31

Lehden numero: 3

Artikkelin sivunumerot: 1523-1537

Kustantaja: Oxford University Press

Julkaisumaa: Yhdysvallat (USA)

Julkaisun kieli: englanti

DOI: https://doi.org/10.1093/cercor/bhaa306

Julkaisun avoin saatavuus: Avoimesti saatavilla

Julkaisukanavan avoin saatavuus: Osittain avoin julkaisukanava

Julkaisu on rinnakkaistallennettu (JYX): https://jyx.jyu.fi/handle/123456789/72595

Tiivistelmä

Proprioceptive paired-stimulus paradigm was used for 30 children (10-17 years) and 21 adult (25-45 years) volunteers in magnetoencephalography (MEG). Their right index finger was moved twice with 500-ms interval every 4 ± 25 s (repeated 100 times) using a pneumatic-movement actuator. Spatial-independent component analysis (ICA) was applied to identify stimulus-related components from MEG cortical responses. Clustering was used to identify spatiotemporally consistent components across subjects. We found a consistent primary response in the primary somatosensory (SI) cortex with similar gating ratios of 0.72 and 0.69 for the children and adults, respectively. Secondary responses with similar transient gating behavior were centered bilaterally in proximity of the lateral sulcus. Delayed and prolonged responses with strong gating were found in the frontal and parietal cortices possibly corresponding to larger processing network of somatosensory afference. No significant correlation between age and gating ratio was found. We confirmed that cortical gating to proprioceptive stimuli is comparable to other somatosensory and auditory domains, and between children and adults. Gating occurred broadly beyond SI cortex. Spatial ICA revealed several consistent response patterns in various cortical regions which would have been challenging to detect with more commonly applied equivalent current dipole or distributed source estimates.

YSO-asiasanat: liikeaisti; ärsykkeet; MEG; signaalianalyysi

Vapaat asiasanat: independent component analysis; magnetoencephalography; paired stimulus; proprioception; somatosensory

Liittyvät organisaatiot

Hankkeet, joissa julkaisu on tehty

OKM-raportointi: Kyllä

Raportointivuosi: 2021

JUFO-taso: 3