A1 Journal article (refereed)
Disability, Health-Related Quality of Life and Mortality in Lumbar Spine Fusion Patients : A 5-Year Follow-Up and Comparison With a Population Sample (2022)

Toivonen, L., Pekkanen, L., Neva, M. H., Kautiainen, H., Kyrölä, K., Marttinen, I., & Häkkinen, A. (2022). Disability, Health-Related Quality of Life and Mortality in Lumbar Spine Fusion Patients : A 5-Year Follow-Up and Comparison With a Population Sample. Global Spine Journal, 12(6), 1052-1057. https://doi.org/10.1177/2192568220972977

JYU authors or editors

Publication details

All authors or editorsToivonen, Leevi; Pekkanen, Liisa; Neva, Marko H.; Kautiainen, Hannu; Kyrölä, Kati; Marttinen, Ilkka; Häkkinen, Arja

Journal or seriesGlobal Spine Journal



Publication year2022

Publication date18/11/2020


Issue number6

Pages range1052-1057

PublisherSAGE Publications

Publication countryUnited Kingdom

Publication languageEnglish


Publication open accessOpenly available

Publication channel open accessOpen Access channel

Publication is parallel published (JYX)https://jyx.jyu.fi/handle/123456789/72756


Study Design:
Prospective follow-up study.
We aimed to assess the effect of lumbar spine fusion (LSF) on disability, health-related quality of life and mortality in a 5-year follow-up, and to compare these results with the general population.
523 consecutive LSF operations were included in a prospective follow-up. Disability was assessed by the Oswestry Disability Index (ODI), and HRQoL by the 36-item Short Form (SF-36) questionnaire using the physical and mental summary scores (PCS and MCS). The patients were compared with an age-, sex-, and residential area matched general population cohort.
The preoperative ODI in the patients was 46 (SD 16), and the change at 5 years was −26 (95% CI: −24 to −28), p < 0.001. In the population, ODI (baseline 13, SD 16) remained unchanged. The preoperative PCS in the patients was 27 (SD 7), in the population 45 (SD 11), and the increase in the patients at 5 years was 8 (95% CI: 7 to 9), p < 0.001. The patients did not reach the population in ODI or PCS. The baseline MCS in the patients was 47 (SD 13), and the change at 5 years 4 (95% CI: 3 to 7), p < 0.001. MCS of the females reached the population at 5-year follow-up. When analyzing short and long fusions separately, comparable changes were seen in both subgroups. There was no difference in mortality between the patients (3.4%) and the population (4.8%), hazard ratio (HR) 0.86.
Although the patients who had undergone LSF benefited from surgery still at 5 years, they never reached the physical level of the population.

Keywordsspinal diseaseslumbar vertebraesurgical treatmentquality of lifemortalityfollow-up study

Free keywordslumbar spinal fusion (LSF); outcome; longer follow-up; population sample; mortality

Contributing organizations

Ministry reportingYes

Reporting Year2023

JUFO rating1

Last updated on 2024-15-06 at 00:46