A1 Journal article (refereed)
Synthesis of novel fluorinated building blocks via halofluorination and related reactions (2020)

Remete, A. M., Novák, T. T., Nonn, M., Haukka, M., Fülöp, F., & Kiss, L. (2020). Synthesis of novel fluorinated building blocks via halofluorination and related reactions. Beilstein Journal of Organic Chemistry, 16, 2562-2575. https://doi.org/10.3762/bjoc.16.208

JYU authors or editors

Publication details

All authors or editors: Remete, Attila Márió; Novák, Tamás T.; Nonn, Melinda; Haukka, Matti; Fülöp, Ferenc; Kiss, Loránd

Journal or series: Beilstein Journal of Organic Chemistry

ISSN: 2195-951X

eISSN: 1860-5397

Publication year: 2020

Volume: 16

Pages range: 2562-2575

Publisher: Beilstein-Institut zur Förderung der Chemischen Wissenschaften

Publication country: Germany

Publication language: English

DOI: https://doi.org/10.3762/bjoc.16.208

Publication open access: Openly available

Publication channel open access: Open Access channel

Publication is parallel published (JYX): https://jyx.jyu.fi/handle/123456789/72834

Publication is parallel published: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590628/


A study exploring halofluorination and fluoroselenation of some cyclic olefins, such as diesters, imides, and lactams with varied functionalization patterns and different structural architectures is described. The synthetic methodologies were based on electrophilic activation through halonium ions of the ring olefin bonds, followed by nucleophilic fluorination with Deoxo-Fluor®. The fluorine-containing products thus obtained were subjected to elimination reactions, yielding various fluorine-containing small-molecular entities.

Keywords: fluorine; organic compounds; chemical synthesis

Free keywords: fluorine; fluoroselenation; functionalization; halofluorination; stereocontrol

Contributing organizations

Ministry reporting: Yes

Reporting Year: 2020

JUFO rating: 1

Last updated on 2022-14-09 at 12:11