A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Human Brain Ages With Hierarchy-Selective Attenuation of Prediction Errors (2021)

Hsu, Y.-F., Waszak, F., Strömmer, J., & Hämäläinen, J. A. (2021). Human Brain Ages With Hierarchy-Selective Attenuation of Prediction Errors. Cerebral Cortex, 31(4), 2156-2168. https://doi.org/10.1093/cercor/bhaa352

JYU-tekijät tai -toimittajat

Julkaisun tiedot

Julkaisun kaikki tekijät tai toimittajat: Hsu, Yi-Fang; Waszak, Florian; Strömmer, Juho; Hämäläinen, Jarmo A.

Lehti tai sarja: Cerebral Cortex

ISSN: 1047-3211

eISSN: 1460-2199

Julkaisuvuosi: 2021

Volyymi: 31

Lehden numero: 4

Artikkelin sivunumerot: 2156-2168

Kustantaja: Oxford University Press

Julkaisumaa: Yhdysvallat (USA)

Julkaisun kieli: englanti

DOI: https://doi.org/10.1093/cercor/bhaa352

Julkaisun avoin saatavuus: Avoimesti saatavilla

Julkaisukanavan avoin saatavuus: Osittain avoin julkaisukanava

Julkaisu on rinnakkaistallennettu (JYX): https://jyx.jyu.fi/handle/123456789/73032

Tiivistelmä

From the perspective of predictive coding, our brain embodies a hierarchical generative model to realize perception, which proactively predicts the statistical structure of sensory inputs. How are these predictive processes modified as we age? Recent research suggested that aging leads to decreased weighting of sensory inputs and increased reliance on predictions. Here we investigated whether this age-related shift from sensorium to predictions occurs at all levels of hierarchical message passing. We recorded the electroencephalography responses with an auditory local–global paradigm in a cohort of 108 healthy participants from 3 groups: seniors, adults, and adolescents. The detection of local deviancy seems largely preserved in older individuals at earlier latency (including the mismatch negativity followed by the P3a but not the reorienting negativity). In contrast, the detection of global deviancy is clearly compromised in older individuals, as they showed worse task performance and attenuated P3b. Our findings demonstrate that older brains show little decline in sensory (i.e., first-order) prediction errors but significant diminution in contextual (i.e., second-order) prediction errors. Age-related deficient maintenance of auditory information in working memory might affect whether and how lower-level prediction errors propagate to the higher level.

YSO-asiasanat: ikääntyminen; havaintopsykologia; havainnot; kuulohavainnot; EEG

Vapaat asiasanat: aging; auditory perception; electroencephalography (EEG); prediction errors; predictive coding

Liittyvät organisaatiot

OKM-raportointi: Kyllä

Raportointivuosi: 2021

JUFO-taso: 3