A1 Journal article (refereed)
Children at risk for dyslexia show deficient left-hemispheric memory representations for new spoken word forms (2021)


Nora, A.; Renvall, H; Ronimus, M.; Kere, J.; Lyytinen, Heikki; Salmelin, R. (2021). Children at risk for dyslexia show deficient left-hemispheric memory representations for new spoken word forms. NeuroImage, 229, 117739. DOI: 10.1016/j.neuroimage.2021.117739


JYU authors or editors


Publication details

All authors or editors: Nora, A.; Renvall, H; Ronimus, M.; Kere, J.; Lyytinen, Heikki; Salmelin, R.

Journal or series: NeuroImage

ISSN: 1053-8119

eISSN: 1095-9572

Publication year: 2021

Volume: 229

Article number: 117739

Publisher: Elsevier BV

Publication country: Netherlands

Publication language: English

DOI: https://doi.org/10.1016/j.neuroimage.2021.117739

Open Access: Publication published in an open access channel

Publication is parallel published (JYX): https://jyx.jyu.fi/handle/123456789/73908


Abstract

Developmental dyslexia is a specific learning disorder with impairments in reading and spelling acquisition. Apart from literacy problems, dyslexics show inefficient speech encoding and deficient novel word learning, with underlying problems in phonological processing and learning. These problems have been suggested to be related to deficient specialization of the left hemisphere for language processing. To examine this possibility, we tracked with magnetoencephalography (MEG) the activation of the bilateral temporal cortices during formation of neural memory traces for new spoken word forms in 7-8-year-old children with high familial dyslexia risk and in controls. The at-risk children improved equally to their peers in overt repetition of recurring new word forms, but were poorer in explicit recognition of the recurring word forms. Both groups showed reduced activation for the recurring word forms 400–1200 ms after word onset in the right auditory cortex, replicating the results of our previous study on typically developing children (Nora et al, 2017, Children show right-lateralized effects of spoken word-form learning. PLoS ONE 12(2): e0171034). However, only the control group consistently showed a similar reduction of activation for recurring word forms in the left temporal areas. The results highlight the importance of left-hemispheric phonological processing for efficient phonological representations and its disruption in dyslexia.


Keywords: dyslexia; language development; language acquisition; phonological awareness; memory (cognition); MEG

Free keywords: dyslexia; reading acquisition; phonological learning; magnetoencephalography


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Ministry reporting: Yes

Preliminary JUFO rating: 2


Last updated on 2021-01-02 at 12:40