A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Glucose regulation and grip strength in adults : findings from the Helsinki Birth Cohort Study (2021)


Åström, M. J., von Bonsdorff, M. B., Salonen, M. K., Kajantie, E., Osmond, C., & Eriksson, J. G. (2021). Glucose regulation and grip strength in adults : findings from the Helsinki Birth Cohort Study. Archives of Gerontology and Geriatrics, 94, Article 104348. https://doi.org/10.1016/j.archger.2021.104348


JYU-tekijät tai -toimittajat


Julkaisun tiedot

Julkaisun kaikki tekijät tai toimittajat: Åström, Max J.; von Bonsdorff, Mikaela B.; Salonen, Minna K.; Kajantie, Eero; Osmond, Clive; Eriksson, Johan G.

Lehti tai sarja: Archives of Gerontology and Geriatrics

ISSN: 0167-4943

eISSN: 1872-6976

Julkaisuvuosi: 2021

Volyymi: 94

Artikkelinumero: 104348

Kustantaja: Elsevier

Julkaisumaa: Irlanti

Julkaisun kieli: englanti

DOI: https://doi.org/10.1016/j.archger.2021.104348

Julkaisun avoin saatavuus: Avoimesti saatavilla

Julkaisukanavan avoin saatavuus: Osittain avoin julkaisukanava

Julkaisu on rinnakkaistallennettu (JYX): https://jyx.jyu.fi/handle/123456789/74017


Tiivistelmä

Aim
: This study aimed to assess the association between grip strength and glucose regulation in a cross-sectional setting.

Methods
: Using data from the Helsinki Birth Cohort Study, 924 men and 953 women were studied at a mean age of 61.6 years. Grip strength was assessed in the dominant hand using a Newtest Grip Force dynamometer. A standard 2-h 75g oral glucose tolerance test (OGTT) was used to define glucose regulation. The participants were classified into four groups: normoglycaemia, prediabetes (impaired fasting glucose or impaired glucose tolerance), newly diagnosed diabetes and previously known diabetes. The association between grip strength and glucose regulation was assessed using multiple linear regression models.

Results
: Prediabetes was diagnosed in 32.2% and diabetes in 8.4% using the OGTT. A total of 7.8% of the individuals had previously known diabetes. Compared to individuals with normoglycaemia, grip strength was lower for those with newly diagnosed diabetes (-1.8kg, 95% CI -3.2 to -0.5) as well as those with previously known diabetes (-1.8kg, 95% CI -3.2 to -0.4) after adjusting for covariates (age, sex, body mass index, physical activity, education and smoking). No difference in grip strength was found when comparing those with prediabetes and normoglycaemia.

Conclusion
: In adults, grip strength was lower among those with known and newly diagnosed diabetes compared to those with normoglycaemia. Together with previous findings on associations between grip strength and chronic diseases, these results support the use of grip strength as an overall health marker in adults.


YSO-asiasanat: epidemiologia; ikääntyminen; diabetes; puristusvoima; fyysinen kunto; kohorttitutkimus

Vapaat asiasanat: diabetes mellitus; epidemiology; grip strength; physical fitness; prediabetes


Liittyvät organisaatiot


OKM-raportointi: Kyllä

Raportointivuosi: 2021

Alustava JUFO-taso: 1


Viimeisin päivitys 2021-02-08 klo 10:19